The current status of beta blockers' use in the management of hypertension.

作者: Mohammad S. Alorainy , Shahid Akbar

DOI:

关键词:

摘要: The invention of beta ( β )-blockers culminated in a new era the treatment cardiovascular diseases (CD), and changed course pharmacology research for years to come. Since introduction propranolol into clinical practice 1964, -blockers enjoyed special place clinicians’ armamentarium against CDs, especially patients with ischemic heart diseases, are still one most extensively used therapeutic drugs both cardiac non-cardiac ailments. Current uses CDs include hypertension, arrhythmias, failure. Other substantial glaucoma, migraine, situational anxiety, benign essential tremors, symptoms thyrotoxicosis. This review covers some evolutionary changes -blockers, rationale their use, recent controversies surrounding use advantages newer additions group.

参考文章(101)
C Ziskoven, R H G Schwinger, K Brixius, W Bloch, C Pott, A Napp, Beta3-adrenergic stimulation in the human heart: signal transduction, functional implications and therapeutic perspectives. Die Pharmazie. ,vol. 61, pp. 255- 260 ,(2006)
Robert Fagard, Reappraisal of the European guidelines on hypertension management: the European Society of Hypertension Task Force document: a short review Polskie Archiwum Medycyny Wewnetrznej-polish Archives of Internal Medicine. ,vol. 120, pp. 31- 35 ,(2010) , 10.20452/PAMW.875
Arthur M. Feldman, Randy Rasmussen, Edward M. Gilbert, Jonathan David Port, Michael R. Bristow, Anthony Sandoval, Andreé E. Cates, Ray E. Hershberger, Beta-adrenergic pathways in nonfailing and failing human ventricular myocardium. Circulation. ,vol. 82, ,(1990)
Jason T. Davis, Dalal N. Pasha, Srikrishna Khandrika, Maple M. Fung, Milos Milic, Daniel T. O’Connor, Central Hemodynamics in Prehypertension: Effect of the β-Adrenergic Antagonist Nebivolol Journal of Clinical Hypertension. ,vol. 15, pp. 69- 74 ,(2013) , 10.1111/JCH.12031
Saskia Bruderer, Michael Bodmer, Susan S. Jick, Christoph R. Meier, Use of Diuretics and Risk of Incident Gout: A Population‐Based Case–Control Study Arthritis & Rheumatism. ,vol. 66, pp. 185- 196 ,(2014) , 10.1002/ART.38203
James Black, Reflections on drug research. British Journal of Pharmacology. ,vol. 161, pp. 1204- 1216 ,(2010) , 10.1111/J.1476-5381.2010.01019.X
Aaron S. Kelly, J. Michael Gonzalez-Campoy, Kyle D. Rudser, Harold Katz, Andrea M. Metzig, Melissa Thalin, Alan J. Bank, Carvedilol-Lisinopril Combination Therapy and Endothelial Function in Obese Individuals With Hypertension Journal of Clinical Hypertension. ,vol. 14, pp. 85- 91 ,(2012) , 10.1111/J.1751-7176.2011.00569.X
S. C. Srivastava, H. A. Dewar, D. J. Newell, Double-blind Trial of Propranolol (Inderal) in Angina of Effort BMJ. ,vol. 2, pp. 724- 725 ,(1964) , 10.1136/BMJ.2.5411.724
Sebastien Czernichow, Alberto Zanchetti, Fiona Turnbull, Federica Barzi, Toshiaru Ninomiya, Andre-Pascal Kengne, Hiddo J Lambers Heerspink, Vlado Perkovic, Rachel Huxley, Hisatomi Arima, Anushka Patel, John Chalmers, Mark Woodward, Stephen MacMahon, Bruce Neal, Blood Pressure Lowering Treatment Trialists' Collaboration, None, The effects of blood pressure reduction and of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure: meta-analysis of randomized trials. Journal of Hypertension. ,vol. 29, pp. 4- 16 ,(2011) , 10.1097/HJH.0B013E32834000BE