Purine Metabolism in Human Thymocyte Subsets: Relevance for Lymphocytic Differentiation
作者： H. J. Schuurman , J. P. R. M. van Laarhoven , R. Broekhuizen , P. Brekelmans , G. Th. Spierenburg
DOI: 10.1007/978-1-4757-0390-0_21
关键词:
摘要: The maturation pathway of the T lymphoid system, from (T) lymphopoietic precursor cell in bone marrow via immature lymphocytes thymus to mature immunocompetent cells peripheral organs and blood, is nowadays well established. Stages differentiation can be distinguished both by expression surface cytoplasmic markers (e.g., phenotyping with monoclonal antibodies lymphocyte (sub)populations1) functional capacity (e.g. differential responsiveness mitogens like phytohaemagglutinin (PHA))2.
springer.com
ru.nl
core.ac.uk
sci-hub.st 参考文章(14)
N Tidman, G Goldstein, G Janossy, S Granger, M Bodger, P C Kung, Delineation of human thymocyte differentiation pathways utilizing double-staining techniques with monoclonal antibodies. Clinical and Experimental Immunology. ,vol. 45, pp. 457- ,(1981)
J Kaye, D A Carson, D B Wasson, Differences in deoxyadenosine metabolism in human and mouse lymphocytes. Journal of Immunology. ,vol. 124, pp. 8- 12 ,(1980)
Jeffrey M. Johnston, Nicholas M. Kredich, Inhibition of Methylation by Adenosine in Adenosine Deaminase-Inhibited, Phytohemagglutinin-Stimulated Human Lymphocytes Journal of Immunology. ,vol. 123, pp. 97- 103 ,(1979)
J Minowada, W P Schrader, B E Chechik, An immunomorphologic study of adenosine deaminase distribution in human thymus tissue, normal lymphocytes, and hematopoietic cell lines. Journal of Immunology. ,vol. 126, pp. 1003- 1007 ,(1981)
H M Dosch, A Cohen, E W Gelfand, J W Lee, The expression of deoxyguanosine toxicity in T lymphocytes at different stages of maturation. Journal of Immunology. ,vol. 125, pp. 1578- 1582 ,(1980)
Carl G. Figdor, Willy S. Bont, Jan E. De Vries, Wim L. Van Es, Isolation of large numbers of highly purified lymphocytes and monocytes with a modified centrifugal elutriation technique Journal of Immunological Methods. ,vol. 40, pp. 275- 288 ,(1981) , 10.1016/0022-1759(81)90359-8
Laure Thuillier, Florianne Garreau, Pierre Cartier, Inability of immunocompetent thymocytes to produce T-cell growth factor under adenosine deaminase deficiency conditions Cellular Immunology. ,vol. 63, pp. 81- 90 ,(1981) , 10.1016/0008-8749(81)90030-7
René van de Griend, Alberto Astaldi, Hein de Bruin, Hans Tanke, Rineke van Doorn, Louis Meerhof, Dirk Roos, Characterization of physically different human T-cell subsets with monoclonal antibodies and biochemical markers. Clinical Immunology and Immunopathology. ,vol. 21, pp. 94- 105 ,(1981) , 10.1016/0090-1229(81)90198-7
Robert Oosterom, Louis Kater, Jonet Oosterom, Effects of human thymic epithelial-conditioned medium on mitogen responsiveness of human and mouse lymphocytes. Clinical Immunology and Immunopathology. ,vol. 12, pp. 460- 470 ,(1979) , 10.1016/0090-1229(79)90051-5
RandallW. Barton, Irving Goldschneider, Nucleotide-metabolizing enzymes and lymphocyte differentiation. Molecular and Cellular Biochemistry. ,vol. 28, pp. 135- 147 ,(1979) , 10.1007/BF00223363