Environmental properties of long-chain alcohols. Part 2: Structure-activity relationship for chronic aquatic toxicity of long-chain alcohols.
作者： C. Schäfers , U. Boshof , H. Jürling , S.E. Belanger , H. Sanderson
DOI: 10.1016/J.ECOENV.2008.07.019
关键词:
摘要: Abstract Daphnia magna reproduction tests were performed with C 10 , 12 14 and 15 alcohols to establish a structure–activity relationship of chronic effects long-chain alcohols. The data generation involved substantial methodological efforts due the exceptionally rapid biodegradability test substances need as close possible their water solubility limits. Test concentrations determined by GC–MS before after solution renewal. Whereas apparent toxicity based on survival increased increasing C-chain lengths up observations alcohol not in line lower chain lack below level solubility. When omitting slope most (Q)SARs approach −1, being consistent expectation non-polar narcotic mode action. Further testing at higher is sensible progressively solubility, remaining biodegradability. Effects mortality are expected
cabdirect.org
elsevier.com
sci-hub.se 参考文章(26)
Beate I. Escher, Joop L. M. Hermens, Modes of action in ecotoxicology: their role in body burdens, species sensitivity, QSARs, and mixture effects. Environmental Science & Technology. ,vol. 36, pp. 4201- 4217 ,(2002) , 10.1021/ES015848H
Renate Kühn, Monika Pattard, Klaus-Dieter Pernak, Angela Winter, Results of the harmful effects of water pollutants to Daphnia magna in the 21 day reproduction test Water Research. ,vol. 23, pp. 501- 510 ,(1989) , 10.1016/0043-1354(89)90142-5
Beate I. Escher, Rik I. L. Eggen, Ulrich Schreiber, Zachariah Schreiber, Erika Vye, Bianca Wisner, René P. Schwarzenbach, Baseline toxicity (narcosis) of organic chemicals determined by in vitro membrane potential measurements in energy-transducing membranes. Environmental Science & Technology. ,vol. 36, pp. 1971- 1979 ,(2002) , 10.1021/ES015844C
S.E. Belanger, P.B. Dorn, R. Toy, G. Boeije, S.J. Marshall, T. Wind, R. Van Compernolle, D. Zeller, Aquatic risk assessment of alcohol ethoxylates in North America and Europe Ecotoxicology and Environmental Safety. ,vol. 64, pp. 85- 99 ,(2006) , 10.1016/J.ECOENV.2005.11.003
Thomas W. Federle, Nina R. Itrich, Fate of free and linear alcohol-ethoxylate-derived fatty alcohols in activated sludge. Ecotoxicology and Environmental Safety. ,vol. 64, pp. 30- 41 ,(2006) , 10.1016/J.ECOENV.2005.05.008
R. van Compernolle, D.C. McAvoy, A. Sherren, T. Wind, M.L. Cano, S.E. Belanger, P.B. Dorn, K.M. Kerr, Predicting the sorption of fatty alcohols and alcohol ethoxylates to effluent and receiving water solids. Ecotoxicology and Environmental Safety. ,vol. 64, pp. 61- 74 ,(2006) , 10.1016/J.ECOENV.2005.10.013
H. Rufli, P.R. Fisk, A.E. Girling, J.M.H. King, R. Länge, X. Lejeune, N. Stelter, C. Stevens, P. Suteau, J. Tapp, J. Thus, D.J. Versteeg, H.J. Niessen, Aquatic Toxicity Testing of Sparingly Soluble, Volatile, and Unstable Substances and Interpretation and Use of Data Ecotoxicology and Environmental Safety. ,vol. 39, pp. 72- 77 ,(1998) , 10.1006/EESA.1997.1612
Hans Könemann, Quantitative structure-activity relationships in fish toxicity studies Part 1: Relationship for 50 industrial pollutants Toxicology. ,vol. 19, pp. 209- 221 ,(1981) , 10.1016/0300-483X(81)90130-X
Hans Könemann, FISH TOXICITY TESTS WITH MIXTURES OF MORE THAN TWO CHEMICALS: A PROPOSAL FOR A QUANTITATIVE APPROACH AND EXPERIMENTAL RESULTS Toxicology. ,vol. 19, pp. 229- 238 ,(1981) , 10.1016/0300-483X(81)90132-3
S.E. Belanger, H. Sanderson, P.R. Fisk, C. Schäfers, S.M. Mudge, A. Willing, Y. Kasai, A.M. Nielsen, S.D. Dyer, R. Toy, Assessment of the environmental risk of long-chain aliphatic alcohols Ecotoxicology and Environmental Safety. ,vol. 72, pp. 1006- 1015 ,(2009) , 10.1016/J.ECOENV.2008.07.013