THE ADRENERGIC SYSTEM AND SYMPATHOMIMETIC AMINES.

摘要: Publisher Summary The sympathomimetic amines adrenaline and noradrenaline, depending on chemical structure, act either directly the adrenergic receptor or rely for their effect integrity of postganglionic neuron chromaffin cells. Noradrenaline, together with a variable but small amount adrenaline, is released after nerve excitation. This chapter suggests that noradrenaline associated sympathetic endings some other possibly Again acts mainly α-receptors, isoprenaline β-receptors, both. adrenal gland major source in body; are liberated excitation its preganglionic innervation. presence sympathin central nervous system may be indicative transmitter role like assigned to ganglia fibers, it modify transmission similar modulating influence at spinal cholinergic synapses. can tested tissue they excite. response smooth muscle should regarded as resultant two opposing actions, so there tissues respond biphasically upon conditions. However, single antipodally predictable fashion not just series structurally different amines. Adrenergic antagonists would inestimable value defining physicochemical properties classifying A large number adrenergic-blocking drugs now available. paradigm each category has been discussed chapter.