Pruritus in Elderly Patients—Eruptions of Senescence

摘要: Geriatric patients are frequently afflicted by pruritic dermatoses. Most elderly present with a skin eruption. The high prevalence of inflammatory disorders in is consequence three physiological changes that occur aging: (1) the epidermal barrier repair diminished; (2) immune systems activated and have defective Th1 function along enhanced Th2 (immunosenescense); (3) neurodegenerative may lead to pruritus their central or peripheral effects. These consequences aging all afflict same patient, explaining why people often multiple overlapping conditions. following article outlines pathogenesis most common forms disease hallmarks allow dermatologist establish an accurate diagnosis also suggests management strategy for each type patient.