A kinetic model of cadmium metabolism in the human being
作者： Tord Kjellström , Gunnar F. Nordberg
DOI: 10.1016/0013-9351(78)90160-3
关键词:
摘要: Abstract An eight-compartment kinetic model for the metabolism of cadmium was formulated based on animal and human tissue distribution data. The flow between compartments generally assumed to follow first-order exponential functions. 21 coefficients were estimated by fitting calculated concentrations in kidney, liver, urine, blood, other tissues observed Swedes with different smoking habits without occupational exposure. Japanese persons also agreed concentrations. used calculate daily intake necessary reach critical concentration kidney cortex. average renal cortex would 200 μg/g at an via food 440 μg a European-American population 325 population.
eurekamag.com
harvard.edu
osti.gov
elsevier.com参考文章(34)
Bates Dv, Hatch Tf, Mercer Tt, Fish Br, Morrow Pe, Deposition and retention models for internal dosimetry of the human respiratory tract. Task group on lung dynamics. Health Physics. ,vol. 12, pp. 173- 207 ,(1966)
Jeremias H.R. Kägi, Bert L. Vallee, Metallothionein: a cadmium- and zinc-containing protein from equine renal cortex. Journal of Biological Chemistry. ,vol. 235, pp. 3460- 3465 ,(1960) , 10.1016/S0021-9258(18)64490-4
Keitaro Nishiyama, Gunnar F. Nordberg, Adsorption and elution of cadmium on hair. Archives of Environmental Health. ,vol. 25, pp. 92- 96 ,(1972) , 10.1080/00039896.1972.10666142
Lars Friberg, Cadmium in the environment ,(1971)
G. F. Nordberg, Effects and dose-response relationships of toxic metals. Effects and dose-response relationships of toxic metals.. ,(1976)
Tord Kjellström, Per-Eric Evrin, Barbro Rahnster, Dose-response analysis of cadmium-induced tubular proteinuria: A study of urinary β2-microglobulin excretion among workers in a battery factory Environmental Research. ,vol. 13, pp. 303- 317 ,(1977) , 10.1016/0013-9351(77)90106-2
Rolf H.O. Bühler, Jeremias H.R. Kägi, Human hepatic metallothioneins. FEBS Letters. ,vol. 39, pp. 229- 234 ,(1974) , 10.1016/0014-5793(74)80057-8
Roy E. Albert, Morton Lippmann, Jack Spiegelman, Anthony Liuzzi, Norton Nelson, The deposition and clearance of radioactive particles in the human lung. Archives of Environmental Health. ,vol. 14, pp. 10- 15 ,(1967) , 10.1080/00039896.1967.10664686
Junko Matsubara-Khan, Kazuhiko Machida, Cadmium accumulation in mouse organs during the sequential injections of cadmium-109 Environmental Research. ,vol. 10, pp. 29- 38 ,(1975) , 10.1016/0013-9351(75)90071-7
Monica Nordberg, Studies on metallothionein and cadmium Environmental Research. ,vol. 15, pp. 381- 404 ,(1978) , 10.1016/0013-9351(78)90120-2