Roles of MicroRNAs and Myocardial Cell Differentiation
作者： Tomohide Takaya , Hitoo Nishi , Takahiro Horie , Koh Ono , Koji Hasegawa
DOI: 10.1016/B978-0-12-398459-3.00006-X
关键词:
摘要: As drug therapy is of limited efficacy in the treatment heart diseases related to loss cardiomyocytes, which have very poor division potential, regenerative medicine expected be a new strategy address cardiac diseases. To achieve myocardial regeneration, elucidation mechanism differentiation from stem cells essential. Myocardial embryonic pluripotent has been investigated worldwide, and remarkable developments such as establishment induced transformation somatic cardiomyocytes recently made, markedly changing medicine. At same time, close involvement microRNA maintenance, proliferation, differentiation, reprogramming these revealed. In this report, outlined, focusing on its role differentiation.
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