[The L-isomer as teratogenic principle of N-phthalyl-DL-glutamic acid].

作者: H. Ockenfels , F. Köhler

DOI: 10.1007/BF01897987

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摘要: The teratogenicity of optical antipodes phthaloyl-glutamic acid, a metabolite thalidomide, was determined by administering i.p. to pregnant mice. injected solution contained Tween 20 as solubilizer. Under the conditions experiment thel-isomer found be embryotoxic; whereas thed-form devoid any embryopathic properties.

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