Five-Year Mortality Hazard Is Reduced In Chronic Obstructive Pulmonary Disease Patients Receiving Double- versus Single-Lung Transplants.
作者： Todd C. Crawford , Cecillia Lui , J. Trent Magruder , Jinny S. Ha , Robert S. Higgins
DOI: 10.1016/J.JSS.2018.04.048
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摘要: Abstract Background Previous studies suggest double-lung transplant (DLT) may be associated with superior survival compared to single-lung transplantation (SLT) in chronic obstructive pulmonary disease (COPD) recipients. The purpose of this study was compare patients COPD undergoing DLT versus SLT since the inception lung allocation score. Methods We used United Network for Organ Sharing database retrospectively identify adult who underwent isolated from 5/4/2005-12/31/2014. then separated into SLT. Short-term (1 y) and long-term (5 y) were between cohorts by method Kaplan–Meier, Cox proportional hazards modeling adjust case mix. Results Four thousand eight hundred thirty-two listed, 3554 over period, including 1358 SLTs (38%) 2196 DLTs (62%). Survival 1 y after listing 93% those remaining wait listed (n = 1892) 91% (n = 1093) 89% (n = 1847) (log-rank P Conclusions In largest analysis recipients score, hazard 5-y mortality significantly reduced as
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