Oxidized albumin is associated with water retention and severity of disease in patients with chronic liver diseases

作者: Masahiro Sakata , Takumi Kawaguchi , Eitaro Taniguchi , Akira Nakayama , Sonoko Ishizaki

DOI: 10.1016/J.ECLNM.2010.09.003

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摘要: Summary Background & aims Serum albumin exists in oxidized and reduced forms. Although oxidation of affects some functions albumin, the involvement disease progression water retention patients with chronic liver remains unclear. The aim this study was to determine whether there is an association between disease. Methods Seventy-nine viral diseases 31 cirrhotic hypoalbuminemia were enrolled. percentage determined by high-performance liquid chromatography. Water assessed extra cellular fluid/total body fluid ratio (ECF/TBF) using a bioelectrical impedance analyzer. Results significantly increased according (chronic hepatitis; 28.3 ± 1.1, Child A; 33.5 ± 1.2, B C; 37.8 ± 1.3, P  Conclusions Oxidized related

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