作者: Kun Lu , Ridwan Mahbub , James G. Fox
DOI: 10.1093/ILAR/ILV018
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摘要: The human body is host to 100 trillion gut microbes, approximately 10-times more than all cells. It estimated that the 500-1000 species residing in encode 150-fold unique genes genome. microbiota has important functions metabolic processing, such as energy production, immune cell development, food digestion, and epithelial homeostasis. been increasingly recognized a dysregulated microbiome contributes significant way variety of diseases, including diabetes, obesity, cardiovascular allergies, inflammatory bowel disease. In particular, accumulating evidence indicates functional interactions between xenobiotics play role mediating chemical toxicity causing or exacerbating This review summarizes emerging illustrates how can affect structure, create changes microbiome, become biotransformed by microbiome.