Mechanisms of Disease: understanding resistance to HER2-targeted therapy in human breast cancer

作者: Rita Nahta , Dihua Yu , Mien-Chie Hung , Gabriel N Hortobagyi , Francisco J Esteva

DOI: 10.1038/NCPONC0509

关键词:

摘要: Trastuzumab is a monoclonal antibody targeted against the human epidermal growth factor receptor (HER) 2 tyrosine kinase receptor, which is overexpressed in approximately 25% of …

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