An emerging role for anti-inflammatory agents for chemoprevention.

作者: Andrew T. Chan , Elmar Detering

DOI: 10.1007/978-3-642-30331-9_1

关键词:

摘要: There have been a number of promising recent developments in the prevention colorectal cancer. This book examines detail important aspects current status and future prospects for chemoprevention tumors, particularly using anti-inflammatory drugs. Research into mechanisms that lead from early adenoma to cancer is discussed. The role modes action available drugs, such as aspirin, celecoxib, sulindac are described data trials aspirin reviewed. In addition, possible impact nutritional agents with properties considered, strategies applicable those high level genetic risk evaluated. An feature its interdisciplinary perspective, offering highly relevant information gastroenterologists, internists, general practitioners, oncologists, gastroenterological surgeons, public health practitioners.

参考文章(24)
Robert Benamouzig, Jacques Deyra, Antoine Martin, Bernard Girard, Eric Jullian, Benoit Piednoir, Daniel Couturier, Thierry Coste, Julian Little, Stanislas Chaussade, Daily soluble aspirin and prevention of colorectal adenoma recurrence: one-year results of the APACC trial. Gastroenterology. ,vol. 125, pp. 328- 336 ,(2003) , 10.1016/S0016-5085(03)00887-4
Robert S. Sandler, Susan Halabi, John A. Baron, Susan Budinger, Electra Paskett, Roger Keresztes, Nicholas Petrelli, J. Marc Pipas, Daniel D. Karp, Charles L. Loprinzi, Gideon Steinbach, Richard Schilsky, A randomized trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer. The New England Journal of Medicine. ,vol. 348, pp. 883- 890 ,(2003) , 10.1056/NEJMOA021633
Andrew T. Chan, Edward L. Giovannucci, Jeffrey A. Meyerhardt, Eva S. Schernhammer, Kana Wu, Charles S. Fuchs, ASPIRIN DOSE AND DURATION OF USE AND RISK OF COLORECTAL CANCER IN MEN Gastroenterology. ,vol. 134, pp. 21- 28 ,(2008) , 10.1053/J.GASTRO.2007.09.035
Jacques Ferlay, Hai-Rim Shin, Freddie Bray, David Forman, Colin Mathers, Donald Maxwell Parkin, Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. International Journal of Cancer. ,vol. 127, pp. 2893- 2917 ,(2010) , 10.1002/IJC.25516
Monica M. Bertagnolli, Craig J. Eagle, Ann G. Zauber, Mark Redston, Scott D. Solomon, KyungMann Kim, Jie Tang, Rebecca B. Rosenstein, Janet Wittes, Donald Corle, Timothy M. Hess, G. Mabel Woloj, Frédéric Boisserie, William F. Anderson, Jaye L. Viner, Donya Bagheri, John Burn, Daniel C. Chung, Thomas Dewar, T. Raymond Foley, Neville Hoffman, Finlay Macrae, Ronald E. Pruitt, John R. Saltzman, Bruce Salzberg, Thomas Sylwestrowicz, Gary B. Gordon, Ernest T. Hawk, Celecoxib for the Prevention of Sporadic Colorectal Adenomas The New England Journal of Medicine. ,vol. 355, pp. 873- 884 ,(2006) , 10.1056/NEJMOA061355
Andrew T. Chan, Shuji Ogino, Charles S. Fuchs, Aspirin and the Risk of Colorectal Cancer in Relation to the Expression of COX-2 The New England Journal of Medicine. ,vol. 356, pp. 2131- 2142 ,(2007) , 10.1056/NEJMOA067208
A. Hallak, L. Alon-Baron, R. Shamir, M. Moshkowitz, B. Bulvik, E. Brazowski, Z. Halpern, N. Arber, Rofecoxib reduces polyp recurrence in familial polyposis. Digestive Diseases and Sciences. ,vol. 48, pp. 1998- 2002 ,(2003) , 10.1023/A:1026130623186
Andrew T Chan, Shuji Ogino, Charles S Fuchs, Aspirin Use and Survival After Diagnosis of Colorectal Cancer JAMA. ,vol. 302, pp. 649- 658 ,(2009) , 10.1001/JAMA.2009.1112
John A. Baron, Bernard F. Cole, Robert S. Sandler, Robert W. Haile, Dennis Ahnen, Robert Bresalier, Gail McKeown-Eyssen, Robert W. Summers, Richard Rothstein, Carol A. Burke, Dale C. Snover, Timothy R. Church, John I. Allen, Michael Beach, Gerald J. Beck, John H. Bond, Tim Byers, E. Robert Greenberg, Jack S. Mandel, Norman Marcon, Leila A. Mott, Loretta Pearson, Fred Saibil, Rosalind U. van Stolk, A randomized trial of aspirin to prevent colorectal adenomas The New England Journal of Medicine. ,vol. 348, pp. 891- 899 ,(2003) , 10.1056/NEJMOA021735