Serum Cholesterol Levels and Six-Year Mortality from Stroke in 350,977 Men Screened for the Multiple Risk Factor Intervention Trial

作者: Hiroyasu Iso , David R. Jacobs , Deborah Wentworth , James D. Neaton , Jerome D. Cohen

DOI: 10.1056/NEJM198904063201405

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摘要: Abstract We examined the relation between serum total cholesterol level and risk of death from stroke during six years follow-up in 350,977 men, 35 to 57 age, who had no history heart attack were not currently being treated for diabetes mellitus. The diagnosis type obtained certificates. Using proportional-hazards regression control cigarette smoking, diastolic blood pressure, race or ethnic group, we found that six-year Intracranial hemorrhage (International Classification Diseases, ninth edition [ICD-9], categories 431 432) was three times higher men with levels under 4.14 mmol per liter (160 mg deciliter) than those (P = 0.05 by omnibus test across five levels). On other hand, a positive association observed nonhemorrhagic 0.007). inverse assoc...

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