Correlation between asparaginase sensitivity and asparagine synthetase protein content, but not mRNA, in acute lymphoblastic leukemia cell lines.
作者： Nan Su , Yuan-Xiang Pan , Mi Zhou , Richard C. Harvey , Stephen P. Hunger
DOI: 10.1002/PBC.21213
关键词:
摘要: … of ASNS in an ASNase-sensitive cell line resulted in enhanced ASNase resistance, and conversely, siRNA-mediated inhibition of ASNS expression promoted increased drug sensitivity. …
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