Congenital tumors of the central nervous system

作者: Mariasavina Severino , Erin S. Schwartz , Majda M. Thurnher , Jana Rydland , Ioannis Nikas

DOI: 10.1007/S00234-010-0699-0

关键词:

摘要: Congenital tumors of the central nervous system (CNS) are often arbitrarily divided into “definitely congenital” (present or producing symptoms at birth), “probably within first week life), and “possibly 6 months life). They represent less than 2% all childhood brain tumors. The clinical features newborns include an enlarged head circumference, associated hydrocephalus, asymmetric skull growth. At birth, a large tense fontanel is presenting sign in up to 85% patients. Neurological as initial comparatively rare. prenatal diagnosis congenital CNS tumors, while based on ultrasonography, has significantly benefited from introduction magnetic resonance imaging studies. Teratomas constitute about one third half these most common neonatal tumor. immature because primitive neural elements and, rarely, component mixed malignant germ cell Other astrocytomas, choroid plexus papilloma, neuroectodermal atypical teratoid/rhabdoid medulloblastomas. Less histologies craniopharyngiomas ependymomas. There strong predilection for supratentorial locations, different infants children. Differential diagnoses spontaneous intracranial hemorrhage that can occur presence coagulation factor deficiency underlying vascular malformations, especially giant heterotopia. prognosis patients with generally poor, usually massive size However, be resected successfully if they small favorably located. favorable outcomes achieved where aggressive surgical treatment leads disease-free survival.

参考文章(112)
Torres Qu, Amacher Al, Rittenhouse S, Congenital medulloblastoma: an inquiry into origins. Childs Nervous System. ,vol. 2, pp. 262- 265 ,(1986) , 10.1007/BF00272500
Norbert Roosen, Martina Deckert, Nikolaus Nicola, Wolfgang Wechsler, Ralf Schober, Hubertus von Voss, Peter Mayer, Christoph Werner, Congenital anaplastic astrocytoma with favorable prognosis. Case report. Journal of Neurosurgery. ,vol. 69, pp. 604- 609 ,(1988) , 10.3171/JNS.1988.69.4.0604
Gollin Sm, Pollack If, Hamilton Rl, Campbell Jw, Finkelstein Sd, Sherwin Rn, Bozik Me, Martinez Aj, The Relationship between TP53 Mutations and Overexpression of p53 and Prognosis in Malignant Gliomas of Childhood Cancer Research. ,vol. 57, pp. 304- 309 ,(1997)
David N. Louis, WHO classification of tumours of the central nervous system International Agency for Research on Cancer. ,(2007)
Askin Seker, M MEMET ÖZEK, None, Congenital glioblastoma multiforme Journal of Neurosurgery: Pediatrics. ,vol. 105, pp. 473- 479 ,(2006) , 10.3171/PED.2006.105.6.473
Korones Dn, Biegel Ja, Khademian Zp, Meyers Sp, Chuang Sh, Zimmerman Ra, Primary Intracranial Atypical Teratoid/Rhabdoid Tumors of Infancy and Childhood: MRI Features and Patient Outcomes American Journal of Neuroradiology. ,vol. 27, pp. 962- 971 ,(2006)
Ilona J. Frieden, PHACE Syndrome Archives of Dermatology. ,vol. 132, pp. 307- 311 ,(1996) , 10.1001/ARCHDERM.1996.03890270083012
W. PAULUS, W. SCHLOTE, E. PERENTES, G. JACOBI, M. WARMUTH-METZ, W. ROGGENDORF, Desmoplastic supratentorial neuroepithelial tumours of infancy Histopathology. ,vol. 21, pp. 43- 49 ,(2007) , 10.1111/J.1365-2559.1992.TB00341.X
Gregor Kaczala, Kenneth Poskitt, Paul Steinbok, Glenda Hendson, Patrice Eydoux, Alfonso Solimano, Neonatal macrocephaly: cerebral primitive neuroectodermal tumor or neuroblastoma as an infrequent cause--a case report and review of the literature. American Journal of Perinatology. ,vol. 24, pp. 507- 509 ,(2007) , 10.1055/S-2007-986698
George A. Alexiou, Kalliopi Stefanaki, George Sfakianos, Neofytos Prodromou, Desmoplastic infantile ganglioglioma: a report of 2 cases and a review of the literature. Pediatric Neurosurgery. ,vol. 44, pp. 422- 425 ,(2008) , 10.1159/000149913