Backrub-like backbone simulation recapitulates natural protein conformational variability and improves mutant side-chain prediction.
作者： Colin A. Smith , Tanja Kortemme
DOI: 10.1016/J.JMB.2008.05.023
关键词:
摘要: … We were interested in selectively sampling backbone motion in specified local regions of the protein while keeping other regions fixed. Therefore, we devised a flexible scheme for …
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