Chimaphilin inhibits human osteosarcoma cell invasion and metastasis through suppressing the TGF-β1-induced epithelial-to-mesenchymal transition markers via PI-3K/Akt, ERK1/2, and Smad signaling pathways.

作者: Feng Dong , Tingting Liu , Hao Jin , Wenbo Wang

DOI: 10.1139/CJPP-2016-0522

关键词:

摘要: Epithelial-to-mesenchymal transition is a cellular process associated with cancer invasion and metastasis. However, the antimetastatic effects of chimaphilin remain elusive. In this study, we attem...

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