Reduced expression of the murine p85α subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes

作者: Michael F. Hirshman , Laurie J. Goodyear , Lewis C. Cantley , David A. Fruman , Franck Mauvais-Jarvis

DOI: 10.1172/JCI13305

关键词:

摘要: … deletion of the Pik3r1 gene on glucose homeostasis in normal … the Pik3r1 gene results in improved insulin signaling and … -fructose 2-kinase (38) and glycogen synthase kinase 3 (39). …

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