Polymorphism of interleukin-10 promoter and tumor necrosis factor receptor II in Vietnamese patients with systemic lupus erythematosus.
作者： Pham Dang Khoa , Tsuyoshi Sugiyama , Takashi Yokochi
DOI: 10.1007/S10067-004-0952-1
关键词:
摘要: The polymorphism of the interleukin-10 (IL-10) promoter and tumor necrosis factor receptor II (TNFRII) in Vietnamese patients with systemic lupus erythematosus (SLE) was examined by using polymerase chain reaction (PCR) method genomic DNA allele-specific primers. In frequency IL-10 1082 genotypes consisting AA, A/G GG, allele G SLE significantly higher than that healthy controls. On other hand, there no statistical difference TNF (TNFR) 196 between It therefore suggested promoter, but not TNFRII, might participate pathogenesis Vietnamese.
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