Advances in the Application of Modified Nucleotides in SELEX Technology
作者： O. M. Antipova , E. G. Zavyalova , A. V. Golovin , G. V. Pavlova , A. M. Kopylov
DOI: 10.1134/S0006297918100024
关键词:
摘要: Aptamers are widely used as molecular recognition elements for detecting and blocking functional biological molecules. Since the common "alphabet" of DNA RNA consists only four letters, chemical diversity aptamers is less than protein built 20 amino acids. Chemical modification nucleotides enlarges potential DNA/RNA aptamers. This review describes latest achievements in a variety approaches to selection with an extended genetic alphabet.
springer.com
sci-hub.se 参考文章(98)
Chun Guo, Christopher P. Watkins, Ryan Hili, Sequence-Defined Scaffolding of Peptides on Nucleic Acid Polymers. Journal of the American Chemical Society. ,vol. 137, pp. 11191- 11196 ,(2015) , 10.1021/JACS.5B07675
K.-U. Schoning, Chemical Etiology of Nucleic Acid Structure: The alpha -Threofuranosyl-(3'rightarrow 2') Oligonucleotide System Science. ,vol. 290, pp. 1347- 1351 ,(2000) , 10.1126/SCIENCE.290.5495.1347
Laure Yatime, Christian Maasch, Kai Hoehlig, Sven Klussmann, Gregers R. Andersen, Axel Vater, Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L- RNA/ L- DNA aptamer Nature Communications. ,vol. 6, pp. 6481- 6481 ,(2015) , 10.1038/NCOMMS7481
J.M. Gregson, P.F. Crain, C.G. Edmonds, R. Gupta, T. Hashizume, D.W. Phillipson, J.A. McCloskey, Structure of the archaeal transfer RNA nucleoside G*-15 (2-amino-4,7-dihydro- 4-oxo-7-beta-D-ribofuranosyl-1H-pyrrolo[2,3-d]pyrimidine-5-carboximi dam ide (archaeosine)). Journal of Biological Chemistry. ,vol. 268, pp. 10076- 10086 ,(1993) , 10.1016/S0021-9258(18)82174-3
Aman P. Mann, Rohan C. Bhavane, Anoma Somasunderam, Brenda Liz Montalvo-Ortiz, Ketan B. Ghaghada, David Volk, René Nieves-Alicea, K. Stephen Suh, Mauro Ferrari, Ananth Annapragada, David G. Gorenstein, Takemi Tanaka, Thioaptamer conjugated liposomes for tumor vasculature targeting. Oncotarget. ,vol. 2, pp. 298- 304 ,(2011) , 10.18632/ONCOTARGET.261
Hongguang Sun, Youli Zu, A Highlight of recent advances in aptamer technology and its application Molecules. ,vol. 20, pp. 11959- 11980 ,(2015) , 10.3390/MOLECULES200711959
Irani Alves Ferreira-Bravo, Christopher Cozens, Philipp Holliger, Jeffrey J. DeStefano, Selection of 2'-deoxy-2'-fluoroarabinonucleotide (FANA) aptamers that bind HIV-1 reverse transcriptase with picomolar affinity Nucleic Acids Research. ,vol. 43, pp. 9587- 9599 ,(2015) , 10.1093/NAR/GKV1057
Fabian Tolle, Gerhard M. Brändle, Daniel Matzner, Günter Mayer, A Versatile Approach Towards Nucleobase‐Modified Aptamers Angewandte Chemie. ,vol. 54, pp. 10971- 10974 ,(2015) , 10.1002/ANIE.201503652
Louis C. Bock, Linda C. Griffin, John A. Latham, Eric H. Vermaas, John J. Toole, Selection of single-stranded DNA molecules that bind and inhibit human thrombin. Nature. ,vol. 355, pp. 564- 566 ,(1992) , 10.1038/355564A0
Anna M. Varizhuk, Vladimir B. Tsvetkov, Olga N. Tatarinova, Dmitry N. Kaluzhny, Vladimir L. Florentiev, Edward N. Timofeev, Anna K. Shchyolkina, Olga F. Borisova, Igor P. Smirnov, Sergei L. Grokhovsky, Anton V. Aseychev, Galina E. Pozmogova, Synthesis, characterization and in vitro activity of thrombin-binding DNA aptamers with triazole internucleotide linkages. European Journal of Medicinal Chemistry. ,vol. 67, pp. 90- 97 ,(2013) , 10.1016/J.EJMECH.2013.06.034