INITIATION OF MITOSIS IN RELATION TO THE CELL CYCLE FOLLOWING FEEDING OF STARVED CHICKENS.

摘要: Cellular proliferation of newly hatched chickens was depressed by starving them for 2.5 to 3.5 days. Starvation may hold proliferative cells in different parts the cell cycle. In order find where cycle these are held, animals were fed and following events measured as a function time after start feeding: (1) mitotic index, (2) DNA synthetic index (number synthesis 1 hour injection H3-thymidine). The duration cell's period (S) measured, permitting more exact description Analysis duodenal esophageal epithelia shows that feeding initiates division stimulating from G1 part duodenum. esophagus some either stopped or slowed down G1, another group G2. Feeding simultaneously stimulates both groups; former moves into S, latter mitosis. S starved is little longer than normally but extension can be attributed slightly decreased body temperature.