The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivo

作者: Dun-Xian Tan , Burkhard Pöeggeler , Russel J. Reiter , Li-Dun Chen , Shou Chen

DOI: 10.1016/0304-3835(93)90076-L

关键词:

摘要: … -adduct formation induced by the chemical carcinogen safrole in a dose-dependent manner. Total DNA-adduct formation after in vivo administration of 300 mg/kg safrole measured by …

参考文章(26)
R. M. Disher, Leejane Lu, K. Randerath, M. V. Reddy, 32P-Postlabeling Assay in Mice of Transplacental DNA Damage Induced by the Environmental Carcinogens Safrole, 4-Aminobiphenyl, and Benzo(a)pyrene Cancer Research. ,vol. 46, pp. 3046- 3054 ,(1986)
Russel J. Reiter, The ageing pineal gland and its physiological consequences. BioEssays. ,vol. 14, pp. 169- 175 ,(1992) , 10.1002/BIES.950140307
Gabriel Hocman, Prevention of cancer: vegetables and plants. Comparative Biochemistry and Physiology B. ,vol. 93, pp. 201- 212 ,(1989) , 10.1016/0305-0491(89)90070-9
Krystyna Frenkel, Carcinogen-mediated oxidant formation and oxidative DNA damage Pharmacology & Therapeutics. ,vol. 53, pp. 127- 166 ,(1992) , 10.1016/0163-7258(92)90047-4
Sidney J. Stohs, Terence A. Lawson, Lucinda Anderson, Ernest Bueding, Effects of oltipraz, BHA, ADT and cabbage on glutathione metabolism, DNA damage and lipid peroxidation in old mice Mechanisms of Ageing and Development. ,vol. 37, pp. 137- 145 ,(1986) , 10.1016/0047-6374(86)90071-0
David E. Blask, Diane B. Pelletier, Steven M. Hill, Athena Lemus-Wilson, David S. Grosso, Sean T. Wilson, Mark E. Wise, Pineal melatonin inhibition of tumor promotion in the N-nitroso-N-methylurea model of mammary carcinogenesis: potential involvement of antiestrogenic mechanisms in vivo. Journal of Cancer Research and Clinical Oncology. ,vol. 117, pp. 526- 532 ,(1991) , 10.1007/BF01613283