Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity

作者: Yun Sok Lee , Jung-whan Kim , Olivia Osborne , Da Young Oh , Roman Sasik

DOI: 10.1016/J.CELL.2014.05.012

关键词:

摘要: Adipose tissue hypoxia and inflammation have been causally implicated in obesity-induced insulin resistance. Here, we report that, early in the course of high-fat diet (HFD) feeding and …

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