INK4a / ARF : A multifunctional tumor suppressor locus

作者: Norman E. Sharpless

DOI: 10.1016/J.MRFMMM.2004.08.021

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摘要: The INK4a/ARF locus encodes two physically linked tumor suppressor proteins, p16INK4a and ARF, which regulate the RB and p53 pathways, respectively. The unusual genomic …

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