Unguisin G, a new kynurenine-containing cyclic heptapeptide from the sponge-associated fungus Aspergillus candidus NF2412

作者: Wei Li , Fang-Wen Jiao , Jia-Qi Wang , Jing Shi , Ting-Ting Wang

DOI: 10.1016/J.TETLET.2020.152322

关键词:

摘要: Abstract One new cyclic heptapeptide containing non-proteinogenic amino acid residues kynurenine and γ-aminobutyric acid, named unguisin G, as well three known congeners unguisins A, E F, were isolated from a sponge-derived fungus Aspergillus candidus NF2412. The structures elucidated by comprehensive spectroscopic analyses of HRESIMS NMR data. absolute configuration 1 was determined advanced Marfey’s method. All compounds evaluated on antimicrobial activities against nine pathogens the agar diffusion

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