Production of Bioactive Deapiosylated Platycosides from Glycosylated Platycosides in Balloon Flower Root Using the Crude Enzyme from the Food-Available Fungus Rhizopus oryzae.

摘要: Extract from balloon flower root (Platycodi radix) containing platycosides as saponins is a beneficial food additive and used for their savory taste the alleviation of respiratory diseases. Deglycosylated show greater pharmacological effects than glycosylated platycosides. However, there are no reports on conversion into deapiosylated In this study, we showed that crude enzyme Rhizopus oryzae, generally recognized safe (GRAS) fungus isolated meju (fermented soybean brick), completely converted in Platycodi radix extract platycosides: platycodin D (deapi-PD), A (deapi-PA), polygalacin (deapi-PGD), platyconic acid (deapi-PCA). Among these, deapi-PA deapi-PCA were first identified using liquid chromatography/mass spectrometry. The anti-inflammatory antioxidant those precursor These could improve properties functional additives.