MULTICENTRE TRIAL OF ETHAMSYLATE FOR PREVENTION OF PERIVENTRICULAR HAEMORRHAGE IN VERY LOW BIRTHWEIGHT INFANTS
作者： JohnW.T Benson , Christine Hayward , JohnP Osborne , JaneF Schulte , MarkR Drayton
DOI: 10.1016/S0140-6736(86)91432-7
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摘要: Abstract The effectiveness of ethamsylate in the prevention periventricular haemorrhage (PVH) very low birthweight infants was evaluated by means a multicentre, placebo-controlled, double-blind trial. In 330 without evidence PVH on initial cranial ultrasound examination there little difference between and placebo groups with respect to subependymal haemorrhage, but intraventricular parenchymal haemorrhages developed 30/162 (18.5%) treated group, compared 50/168 (29.8%) control group (p
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