Physiologic Mechanisms of Therapeutic Resistance: Blood Flow and Hypoxia

作者: Beverly A. Teicher

DOI: 10.1016/S0889-8588(18)30105-9

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摘要: The tools now are available to characterize oxygenation/hypoxia in the clinic. clinical investigations conducted thus far have shown that significant regions of hypoxia exist solid tumors patients. Of various strategies developed laboratory for reducing (or eliminating) tumors, intravenous administration nontoxic oxygen-carrying materials is probably most generally applicable a setting.

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