Magnetic Resonance Imaging of Cancer Therapy

摘要: Newly emerging anticancer strategies have been fostered by recent advances in cancer molecular biology and pharmacology as well imaging technologies, particularly magnetic resonance (MRI) because of its radiation-free safety, superb spatial-contrast-temporal resolutions, versatile applicability for theranostic management innovation. In this chapter, we focus mainly on targeted therapy minimally invasive two representative regimens to highlight the indispensible role MRI clinical experimental oncology. A brief introduction is given conventional techniques therapy. has established a powerful tool not only applications such making diagnosis, monitoring therapeutic response, predicting patient prognosis, but also preclinical utilities including translational development new antitumor evaluation drugs. Now, multiparametric evolved into paradigm with derivative biomarkers characterize tumor structure, cell density, blood volume/flow, vessel permeability, viable/necrotic components, metabolic changes. Comprehensive information thus acquired used vivo observation, evaluation, comparison response investigational treatments Implementing contrast agents further strengthened broadened capacity scope MRI. For instance, use necrosis avid agents, may specifically detect early after treatment. An elaborated platform developing theranostics based described.