Effects of repeated cue exposure on cannabis craving

作者: Jessica S. Fogel , T.H. Kelly , Arit M. Harvanko , Joshua Lile

DOI: 10.1016/J.DRUGALCDEP.2015.07.1111

关键词:

摘要: OF THESIS EFFECTS REPEATED CUE EXPOSURE ON CANNBIS CRAVING Craving is a key element of the cannabis withdrawal syndrome that has been associated with continued use and relapse. Although cue-induced craving established in single laboratory sessions, procedures to sustain over multiple sessions are needed. The purpose present study was determine if responses could be elicited same subjects across sessions. It hypothesized exposure cues would produce more robust than neutral will sustained cue exposures. Five experimental (1 4 cannabis) were conducted. assessed Marijuana Questionnaire (MCQ) Short Form, Visual Analog Scale (VAS), Subject-Rated Physiological Questionnaire, blood pressure, heart rate. Results revealed significant effects initial on VAS measures relative condition. No differences found MCQ composite scores or physiological measures. following not maintained There need for better understanding factors contribute drug despite quit attempts.

参考文章(98)
R N Ehrman, A V Hole, A T McLellan, C P O'Brien, A R Childress, S J Robbins, Cue reactivity and cue reactivity interventions in drug dependence NIDA research monograph. ,vol. 137, pp. 73- 95 ,(1993)
Stephens R Steinberg, KL, Babor, TF, Miller, M, Kadden, R, Duresky, D, None, Brief counseling for marijuana dependence: a manual for treating adults. Center for Substance Abuse Treatment, Substance Abuse and Mental Health Services Administration. ,(2005)
Daniel P. Sulmasy, Neil D. Weinstein, Lynn A. Jansen, Paul S. Appelbaum, William M. P. Klein, Jessica S. Fogel, William Cook, Unrealistic optimism in early-phase oncology trials. IRB: Ethics & Human Research. ,vol. 33, pp. 1- 8 ,(2011)
Robert H. Roth, Floyd E. Bloom, Susan Iversen, Leslie Iversen, Introduction to Neuropsychopharmacology ,(2008)
Pineda J, Ugedo L, Ruiz-Ortega Ja, Receptor Reserve and Turnover of Alpha-2 Adrenoceptors that Mediate the Clonidine-Induced Inhibition of Rat Locus Coeruleus Neurons In Vivo Journal of Pharmacology and Experimental Therapeutics. ,vol. 281, pp. 690- 698 ,(1997)
Elizabeth J. Santa Ana, James J. Prisciandaro, Michael E. Saladin, Aimee L. McRae‐Clark, Stephanie R. Shaftman, Paul J. Nietert, Kathleen T. Brady, D‐cycloserine combined with cue exposure therapy fails to attenuate subjective and physiological craving in cocaine dependence American Journal on Addictions. ,vol. 24, pp. 217- 224 ,(2015) , 10.1111/AJAD.12191
Jennifer McLaren, Wendy Swift, Paul Dillon, Steve Allsop, Cannabis potency and contamination: a review of the literature Addiction. ,vol. 103, pp. 1100- 1109 ,(2008) , 10.1111/J.1360-0443.2008.02230.X
Stephen Sidney, Cardiovascular consequences of marijuana use. The Journal of Clinical Pharmacology. ,vol. 42, ,(2002) , 10.1002/J.1552-4604.2002.TB06005.X
Ryan Vandrey, Maxine L. Stitzer, Miriam Z. Mintzer, Marilyn A. Huestis, Jeannie A. Murray, Dayong Lee, The dose effects of short-term dronabinol (oral THC) maintenance in daily cannabis users. Drug and Alcohol Dependence. ,vol. 128, pp. 64- 70 ,(2013) , 10.1016/J.DRUGALCDEP.2012.08.001
Jane R. Taylor, Peter Olausson, Jennifer J. Quinn, Mary M. Torregrossa, Targeting extinction and reconsolidation mechanisms to combat the impact of drug cues on addiction. Neuropharmacology. ,vol. 56, pp. 186- 195 ,(2009) , 10.1016/J.NEUROPHARM.2008.07.027