Novel sodium channel antagonists in the treatment of neuropathic pain
作者： Mirko Rivara , Valentina Zuliani
DOI: 10.1517/13543784.2016.1121992
关键词:
摘要: ABSTRACTIntroduction: Effective and safe drugs for the treatment of neuropathic pain are still an unmet clinical need. Neuropathic pain, caused by a lesion or disease that affects somatosensory system, is debilitating hampering condition has great economic cost and, above all, tremendous impact on quality life. Sodium channels one major players in generating propagating action potentials. They represent appealing target researchers involved development new safer useful pain. The actual goal to sodium selectively stop abnormal signaling characterizes while leaving normal functions intact.Areas covered: This review covers most recent publications regarding channel blockers their as treatments main areas discussed natural sources blockers, such venom extracts ...
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