Essential fatty acids in the plasma phospholipids of patients with atopic eczema.
作者： M.S. MANKU , D.F. HORROBIN , N.L. MORSE , S. WRIGHT , J.L. BURTON
DOI: 10.1111/J.1365-2133.1984.TB04698.X
关键词:
摘要: We have measured all the essential fatty acids (EFA) in plasma phospholipids forty-one adults with atopic eczema and fifty normal controls. The major dietary n-6 EFA, linoleic acid, was significantly elevated, but its metabolites, 18:3n-6, 20:3n-6, 20:4n-6, 22:4n-6, 22:5n-6 were reduced. n-3 alpha-linolenic also though not significantly, while metabolites These observations suggest that is associated any defect of EFA intake, abnormal metabolism, possibly involving enzyme delta-6-desaturase. Treatment oral evening primrose oil produced partial correction abnormality, had no effect on EFAs.
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