Efficacy and cost of risk-adapted follow-up in patients after colorectal cancer surgery: a prospective, randomized and controlled trial.

摘要: Aims: This paper aims to evaluate the diagnostic efficacy and costs of follow-up tailored according risk recurrence compared with minimal surveillance. Methods: A total 358 patients treated by surgery alone for colorectal cancer were prospectively divided into two groups 200 158 considered at high low respectively, prognostic factors. They further randomized subgroups: group 1, 192 undergoing risk-adapted follow-up, intensive low-intensity; 2, 145 Twenty-one cases dropped out. Median was 61.5 months 42 (intensive follow-up) (low-intensity respectively. Results: At end study, 52.6% 57.2% had developed recurrence. In risk, a significant difference in incidence curative re-operations observed between subgroups surveillance (P<0.05). The actuarial 5 year survival is significantly better than that follow-up. economic 34 57 low-intensity who free from disease after primary very similar. Conclusions: Risk-adapted has improved targeting overall independently allowed reduction following up disease-free patients.