Andreas Kraemer
机构: Group Leader, Structural Genomics Consortium
每年引用次数
引用次数
引用: 921
H-指数: 16
I10-指数 : 21
出版物: 56
Strukturelle Untersuchung Histon-Deacetylase-ähnlicher Enzyme aus Pseudomonas aeruginosa
Andreas Krämer
2017
Development of a potent and selective chemical probe for the pleiotropic kinase CK2.
Laszlo Gyenis , David W. Litchfield , Stefan Knapp , Stefan Knapp
Chemistry & Biology 28 ( 4)
34
2021
Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapy.
Andreas C Joerger , Andreas C Joerger , Stefan Knapp , Marek Wanior
Oncogene 40 ( 21) 3637 -3654
2021
Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders.
Dalia Barsyte-Lovejoy , Dalia Barsyte-Lovejoy , Christoph Sotriffer , Cheryl H Arrowsmith
Journal of Medicinal Chemistry
2021
Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm.
Matthias R. Bauer , Andreas Krämer , Giovanni Settanni , Rhiannon N. Jones
ACS Chemical Biology 15 ( 3) 657 -668
7
2020
Development of a chemical probe against NUDT15
Si Min Zhang , Matthieu Desroses , Anna Hagenkort , Nicholas C. K. Valerie
Nature Chemical Biology 16 ( 10) 1120 -1128
1
2020
Structural and functional characterization of 4-hydroxyphenylpyruvate dioxygenase from the thermoacidophilic archaeon Picrophilus torridus.
Eduard Frick , Thomas Spatzal , Stefan Gerhardt , Andreas Krämer
Extremophiles 18 ( 4) 641 -651
1
2014
Crystal Structure of a Histone Deacetylase Homologue from Pseudomonas aeruginosa.
Andreas Krämer , Thomas Wagner , Özkan Yildiz , Franz-Josef Meyer-Almes
Biochemistry 55 ( 49) 6858 -6868
2016
Toward Photopharmacological Antimicrobial Chemotherapy Using Photoswitchable Amidohydrolase Inhibitors.
Claire E. Weston , Andreas Krämer , Felix Colin , Özkan Yildiz
ACS Infectious Diseases 3 ( 2) 152 -161
36
2017
Perfluorinated hydroxamic acids are potent and selective inhibitors of HDAC-like enzymes from Pseudomonas aeruginosa
Christian Meyners , Benjamin Wolff , Alexander Kleinschek , Andreas Krämer
Bioorganic & Medicinal Chemistry Letters 27 ( 7) 1508 -1512
3
2017
Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis.
Marek Wanior , Franziska Preuss , Xiaomin Ni , Andreas Krämer
Journal of Medicinal Chemistry 63 ( 23) 14680 -14699
10
2020
Substrate specificity and function of acetylpolyamine amidohydrolases from Pseudomonas aeruginosa
Andreas Krämer , Jan Herzer , Joerg Overhage , Franz-Josef Meyer-Almes
BMC Biochemistry 17 ( 1) 4 -4
8
2016
A chemical toolbox for the study of bromodomains and epigenetic signaling
Qin Wu , David Heidenreich , Stanley Zhou , Suzanne Ackloo
Nature Communications 10 ( 1) 1915 -1915
31
2019
Involvement of a Novel Class C Beta-Lactamase in the Transglutaminase Mediated Cross-Linking Cascade of Streptomyces mobaraensis DSM 40847
Stephan Zindel , Vera Ehret , Marina Ehret , Madeleine Hentschel
PLOS ONE 11 ( 2) e0149145
7
2016
A fluorescence lifetime-based binding assay for acetylpolyamine amidohydrolases from Pseudomonas aeruginosa using a [1,3]dioxolo[4,5-f][1,3]benzodioxole (DBD) ligand probe.
Christian Meyners , Robert Wawrzinek , Andreas Krämer , Steffen Hinz
Analytical and Bioanalytical Chemistry 406 ( 20) 4889 -4897
18
2014
Selective targeting of the αC and DFG-out pocket in p38 MAPK.
Sandra Röhm , Martin Schröder , Jessica E. Dwyer , Caroline S. Widdowson
European Journal of Medicinal Chemistry 208 112721
8
2020
Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor
Andreas Krämer , Christian Georg Kurz , Benedict-Tilman Berger , Ibrahim Ethem Celik
European Journal of Medicinal Chemistry 208 112770
1
2020
The thermodynamic signature of ligand binding to histone deacetylase-like amidohydrolases is most sensitive to the flexibility in the L2-loop lining the active site pocket
Christian Meyners , Andreas Krämer , Özkan Yildiz , Franz-Josef Meyer-Almes
Biochimica et Biophysica Acta 1861 ( 7) 1855 -1863
4
2017
Covalent inhibition of histone deacetylase 8 by 3,4-dihydro-2H-pyrimido[1,2-c][1,3]benzothiazin-6-imine
Marius Muth , Niklas Jänsch , Aleksandra Kopranovic , Andreas Krämer
Biochimica et Biophysica Acta (BBA) - General Subjects 1863 ( 3) 577 -585
2019
IPP/CNRS-A017: A chemical probe for human dihydroorotate dehydrogenase (hDHODH)
Andreas Krämer , Amelie Tjaden , Benardina Ndreshkjana , Claudia Tredup
Current Research in Chemical Biology 2 100034
2022
Stefan Knapp Andreas C. Joerger Franz-Josef Meyer-Almes Benedict-Tilman Berger Cheryl Arrowsmith David Heidenreich Claire E. Weston Matthias Baud Christian Meyners Oleg Fedorov Masoud Vedadi Qin Wu Dr. Stanley Zhou, PhD Mathieu Lupien, Ph.D. Kiran Nakka S Ackloo Panagis Filippakopoulos Genevieve Deblois Alan Fersht John Spencer