Eusebio Manchado
机构: Research Scholar, Memorial Sloan Kettering Cancer Center (MSKCC)
每年引用次数
引用次数
引用: 3,987
H-指数: 19
I10-指数 : 21
出版物: 33
SHP2 Inhibition Overcomes RTK-Mediated Pathway Reactivation in KRAS-Mutant Tumors Treated with MEK Inhibitors.
Hengyu Lu , Chen Liu , Roberto Velazquez , Hongyun Wang
Molecular Cancer Therapeutics 18 ( 7) 1323 -1334
25
2019
Targeting Mitotic Exit Leads to Tumor Regression In Vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ Phosphatase
Eusebio Manchado , María Guillamot , Guillermo de Cárcer , Manuel Eguren
Cancer Cell 18 ( 6) 641 -654
165
2010
Kinase Regulation of Human MHC Class I Molecule Expression on Cancer Cells
Elliott J. Brea , Claire Y. Oh , Eusebio Manchado , Sadna Budhu
Cancer immunology research 4 ( 11) 936 -947
73
2016
A pipeline for drug target identification and validation
Eusebio Manchado , Chun-Hao Huang , Nilgun Tasdemir , Darjus F. Tschaharganeh
Cold Spring Harbor Symposia on Quantitative Biology 81 ( 1) 257 -267
10
2016
The anaphase-promoting complex/cyclosome (APC/C): cell-cycle-dependent and -independent functions.
Eusebio Manchado , Manuel Eguren , Marcos Malumbres
Biochemical Society Transactions 38 ( 1) 65 -71
137
2010
Non-mitotic functions of the Anaphase-Promoting Complex
Manuel Eguren , Eusebio Manchado , Marcos Malumbres
Seminars in Cell & Developmental Biology 22 ( 6) 572 -578
50
2011
Targeting Aneuploidy for Cancer Therapy
Eusebio Manchado , Marcos Malumbres
Cell 144 ( 4) 465 -466
24
2011
USP39 Deubiquitinase Is Essential for KRAS Oncogene-driven Cancer.
Julia M. Fraile , Eusebio Manchado , Amaia Lujambio , Víctor Quesada
Journal of Biological Chemistry 292 ( 10) 4164 -4175
23
2017
Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer.
Kevin P O'Rourke , Evangelia Loizou , Geulah Livshits , Emma M Schatoff
Nature Biotechnology 35 ( 6) 577 -582
189
2017
Abstract C54: Pdgfrb is an essential mediator of p53(mut)-driven metastasis in pancreatic cancer
Susann Weissmueller , Michael Saborowski , Eusebio Manchado , Vishal Thapar
Cancer Research 73
2
2013
Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer
Mónica Álvarez-Fernández , María Sanz-Flores , Belén Sanz-Castillo , María Salazar-Roa
Cell Death & Differentiation 25 ( 5) 828 -840
54
2017
Conditional Reverse Tet-Transactivator Mouse Strains for the Efficient Induction of TRE-Regulated Transgenes in Mice
Lukas E. Dow , Zeina Nasr , Michael Saborowski , Saya H. Ebbesen
PLoS ONE 9 ( 4) e95236
42
2014
Mutant p53 drives pancreatic cancer metastasis through cell-autonomous PDGF receptor β signaling.
Susann Weissmueller , Eusebio Manchado , Michael Saborowski , John P. Morris
Cell 157 ( 2) 382 -394
453
2014
Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription
María Guillamot , Eusebio Manchado , Massimo Chiesa , Gonzalo Gómez-López
Scientific Reports 1 ( 1) 189 -189
31
2011
Modeling lung cancer with CRISPR/Cas9
Joana A. Vidigal , Danilo Maddalo , Eusebio Manchado , Carla P. Concepcion
Journal of Thoracic Oncology 11 ( 2)
2016
NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination.
Marcus Ruscetti , Josef Leibold , Matthew J. Bott , Myles Fennell
Science 362 ( 6421) 1416 -1422
220
2018
Genomic Stability and Tumour Suppression by the APC/C Cofactor Cdh1
Irene García-Higuera , Eusebio Manchado , Pierre Dubus , Marta Cañamero
Nature Cell Biology 10 ( 7) 802 -811
370
2008
A combinatorial strategy for treating KRAS-mutant lung cancer
Eusebio Manchado , Susann Weissmueller , John P. Morris , Chi-Chao Chen
Nature 534 ( 7609) 647 -651
211
2016
In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system
Danilo Maddalo , Eusebio Manchado , Carla P. Concepcion , Ciro Bonetti
Nature 516 ( 7531) 423 -427
649
2014
The APC/C cofactor Cdh1 prevents replicative stress and p53-dependent cell death in neural progenitors
Manuel Eguren , Eva Porlan , Eusebio Manchado , Irene García-Higuera
Nature Communications 4 ( 1) 2880
38
2013