Advances in genetic circuit design: novel biochemistries, deep part mining, and precision gene expression.

Alec AK Nielsen , Thomas H Segall-Shapiro , Christopher A Voigt
Current Opinion in Chemical Biology 17 ( 6) 878 -892

108
2013
Programming Escherichia coli to function as a digital display.

Jonghyeon Shin , Shuyi Zhang , Bryan S Der , Alec AK Nielsen
Molecular Systems Biology 16 ( 3)

17
2020
Multi-input CRISPR/Cas genetic circuits that interface host regulatory networks

Alec AK Nielsen , Christopher A Voigt
Molecular Systems Biology 10 ( 11) 763 -763

178
2014
Genetic circuit characterization and debugging using RNA-seq.

Thomas E Gorochowski , Amin Espah Borujeni , Yongjin Park , Alec AK Nielsen
Molecular Systems Biology 13 ( 11) 952 -952

41
2017
Guide-rna expression system for a host cell

Eric Mosher Young , Amar Ghodasara , René Verwaal , Johannes Andries Roubos

2023
A guide-rna expression system for a host cell

Eric Mosher Young , Amar Ghodasara , René Verwaal , Johannes Andries Roubos

2020
Biomolecular and computational frameworks for genetic circuit design

Alec AK Nielsen
Massachusetts Institute of Technology

3
2017
Genetic circuit design automation

A. A. K. Nielsen , B. S. Der , J. Shin , P. Vaidyanathan
Science 352 ( 6281)

887
2016
Characterization of 582 natural and synthetic terminators and quantification of their design constraints

Ying-Ja Chen , Peng Liu , Alec A K Nielsen , Jennifer A N Brophy
Nature Methods 10 ( 7) 659 -664

289
2013
Permanent genetic memory with >1-byte capacity.

Lei Yang , Alec A K Nielsen , Jesus Fernandez-Rodriguez , Conor J McClune
Nature Methods 11 ( 12) 1261 -1266

141
2014
Genomic mining of prokaryotic repressors for orthogonal logic gates.

Brynne C Stanton , Alec A K Nielsen , Alvin Tamsir , Kevin Clancy
Nature Chemical Biology 10 ( 2) 99 -105

247
2014
Provisional BioBrick Language (PoBoL)

Michal Galdzicki , Deepak Chandran , Alec Nielsen , Jason Morrison

4
2009
Bbf rfc 31: Provisional biobrick language (pobol)

Michal Galdzicki , Deepak Chandran , Alec Nielsen , Jason Morrison
Tech. Rep

5
2009
Technological challenges and milestones for writing genomes

Nili Ostrov , Jacob Beal , Tom Ellis , D. Benjamin Gordon
Science 366 ( 6463) 310 -312

24
2019
Cellular checkpoint control using programmable sequential logic

Lauren B. Andrews , Alec A. K. Nielsen , Christopher A. Voigt
Science 361 ( 6408)

88
2018
DNA Assembly in 3D Printed Fluidics

William G. Patrick , Alec A. K. Nielsen , Steven J. Keating , Taylor J. Levy
PLOS ONE 10 ( 12)

31
2015
Deep learning to predict the lab-of-origin of engineered DNA

Alec A. K. Nielsen , Christopher A. Voigt
Nature Communications 9 ( 1) 3135 -3135

31
2018
Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage.

Amin Espah Borujeni , Jing Zhang , Hamid Doosthosseini , Alec A. K. Nielsen
Nature Communications 11 ( 1) 5001 -5001

7
2020
A guide-rna expression system for a host cell

Bianca Elisabeth Maria Gielesen , René Verwaal , Brenda Vonk , Alec A.K. Nielsen

8
2017