Barbara Weir
机构: Principal Scientist, Janssen R&D
每年引用次数
引用次数
引用: 48,282
H-指数: 52
I10-指数 : 62
出版物: 85
"Lineage addiction" in human cancer: lessons from integrated genomics.
L.A. GARRAWAY , B.A. WEIR , X. ZHAO , H. WIDLUND
Cold Spring Harbor Symposia on Quantitative Biology 70 25 -34
28
2005
Somatic Genome Alterations in Human Cancer
MATTHEW L MEYERSON , GAD GETZ , WENDY WINCKLER , RAMEEN BEROUKHIM
The landscape of somatic copy-number alteration across human cancers
Rameen Beroukhim , Craig H Mermel , Dale Porter , Guo Wei
PMC
3,811
2010
Prognostic and Predictive Gene Signature for Adjuvant Chemotherapy in Resected Non–Small-Cell Lung Cancer
Chang-Qi Zhu , Keyue Ding , Dan Strumpf , Barbara A. Weir
Journal of Clinical Oncology 28 ( 29) 4417 -4424
352
2010
Amplification of chromosomal segment 4q12 in non-small cell lung cancer
Alex H. Ramos , Amit Dutt , Craig Mermel , Sven Perner
Cancer Biology & Therapy 8 ( 21) 2042 -2050
99
2009
The EMT regulator ZEB2 is a novel dependency of human and murine acute myeloid leukemia
Hubo Li , Brenton G. Mar , Huadi Zhang , Rishi V. Puram
Blood 129 ( 4) 497 -508
47
2017
Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma
Alyssa L. Kennedy , Mounica Vallurupalli , Liying Chen , Brian Crompton
Oncotarget 6 ( 30) 30178 -30193
42
2015
The Tyrosine Kinase Adaptor Protein FRS2 Is Oncogenic and Amplified in High-Grade Serous Ovarian Cancer
Leo Y. Luo , Eejung Kim , Hiu Wing Cheung , Barbara A. Weir
Molecular Cancer Research 13 ( 3) 502 -509
19
2015
Identification of an “Exceptional Responder” Cell Line to MEK1 Inhibition: Clinical Implications for MEK-Targeted Therapy
Hugh S. Gannon , Nathan Kaplan , Aviad Tsherniak , Francisca Vazquez
Molecular Cancer Research 14 ( 2) 207 -215
14
2016
Characterizing the cancer genome in lung adenocarcinoma
Gad Getz , Sven Perner , Li Ding , Rameen Beroukhim
Nature 450 ( 7171) 893 -898
1,238
2007
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
David A. Barbie , Pablo Tamayo , Jesse S. Boehm , So Young Kim
Nature 462 ( 7269) 108 -112
2,478
2009
PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR
Martin L. Sos , Mirjam Koker , Barbara A. Weir , Stefanie Heynck
Cancer Research 69 ( 8) 3256 -3261
619
2009
MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells.
Gregory V. Kryukov , Frederick H. Wilson , Jason R. Ruth , Joshiawa Paulk
Science 351 ( 6278) 1214 -1218
356
2016
In situ evidence of KRAS amplification and association with increased p21 levels in non-small cell lung carcinoma.
Patrick L. Wagner , Sven Perner , David S. Rickman , Christopher J. LaFargue
American Journal of Clinical Pathology 132 ( 4) 500 -505
18
2009
Small-molecule targeting of brachyury transcription factor addiction in chordoma.
Tanaz Sharifnia , Mathias J. Wawer , Ting Chen , Qing-Yuan Huang
Nature Medicine 25 ( 2) 292 -300
43
2019
Integrative Analysis of 1q23.3 Copy-Number Gain in Metastatic Urothelial Carcinoma
Markus Riester , Lillian Werner , Joaquim Bellmunt , Shamini Selvarajah
Clinical Cancer Research 20 ( 7) 1873 -1883
30
2014
Resistance to CDK2 Inhibitors Is Associated with Selection of Polyploid Cells in CCNE1-Amplified Ovarian Cancer
Dariush Etemadmoghadam , George Au-Yeung , Meaghan Wall , Chris Mitchell
Clinical Cancer Research 19 ( 21) 5960 -5971
66
2013
Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway
Courtney A. Lovejoy , Wendi Li , Steven Reisenweber , Supawat Thongthip
PLoS Genetics 8 ( 7) e1002772 -16
542
2012
Amplification of CRKL Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non–Small Cell Lung Cancers
Hiu Wing Cheung , Jinyan Du , Jesse S. Boehm , Frank He
Cancer Discovery 1 ( 7) 608 -625
99
2011
Systematic Interrogation of 3q26 Identifies TLOC1 and SKIL as Cancer Drivers
Daniel Hagerstrand , Alexander Tong , Steven E. Schumacher , Nina Ilic
Cancer Discovery 3 ( 9) 1044 -1057
52
2013