Barbara Weir
机构: Principal Scientist, Janssen R&D
每年引用次数
引用次数
引用: 48,282
H-指数: 52
I10-指数 : 62
出版物: 85
Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting
David E. Root , Aviad Tsherniak , William C. Hahn , Andrew J. Aguirre
Cancer Discovery 6 ( 8) 914 -929
342
2016
PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer
Jessie Hao-Ru Hsu , Benjamin Hubbell-Engler , Guillaume Adelmant , Jialiang Huang
Cancer Research 77 ( 17) 4613 -4625
14
2017
Computational correction of copy-number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells
Robin M Meyers , Jordan G Bryan , James M McFarland , Barbara A Weir
bioRxiv 160861
1,220
2017
Clinical significance of TTF-1 protein expression and TTF-1 gene amplification in lung adenocarcinoma.
Justine A. Barletta , Sven Perner , A. John Iafrate , Beow Y. Yeap
Journal of Cellular and Molecular Medicine 13 1977 -1986
83
2009
Predicting drug susceptibility of non–small cell lung cancers based on genetic lesions
Martin L. Sos , Kathrin Michel , Thomas Zander , Jonathan Weiss
Journal of Clinical Investigation 119 ( 6) 1727 -1740
248
2009
Mmd1p, a Novel, Conserved Protein Essential for Normal Mitochondrial Morphology and Distribution in the Fission Yeast Schizosaccharomyces pombe
Barbara A. Weir , Michael P. Yaffe
Molecular Biology of the Cell 15 ( 4) 1656 -1665
58
2004
PIK3CA mutant tumors depend on oxoglutarate dehydrogenase
Nina Ilic , Kıvanç Birsoy , Andrew J. Aguirre , Nora Kory
Proceedings of the National Academy of Sciences of the United States of America 114 ( 17)
21
2017
A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines
Yulia Newton , Sam Ng , Zhi Nie , Thea C. Norman
Cell systems 5 ( 5) 485 -497
12
2017
Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors.
Elaine M. Oberlick , Matthew G. Rees , Brinton Seashore-Ludlow , Francisca Vazquez
Cell Reports 28 ( 9) 2331
25
2019
Defining a Cancer Dependency Map
Aviad Tsherniak , Francisca Vazquez , Phil G. Montgomery , Barbara A. Weir
Cell 170 ( 3) 564 -576
1,456
2017
Next-generation characterization of the Cancer Cell Line Encyclopedia
Amanda L. Creech , Allison C. Warren , James M. McFarland , Mahdi Zamanighomi
Nature 569 ( 7757) 503 -508
1,689
2019
Homozygous Deletions and Chromosome Amplifications in Human Lung Carcinomas Revealed by Single Nucleotide Polymorphism Array Analysis
Xiaojun Zhao , Barbara A. Weir , Thomas LaFramboise , Ming Lin
Cancer Research 65 ( 13) 5561 -5570
363
2005
Towards patient-based cancer therapeutics
Cancer Target Discovery and Development Network , Stuart L Schreiber , Alykhan F Shamji , Paul A Clemons
Nature Biotechnology 28 ( 9) 904 -906
69
2010
High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines
Channing Yu , Aristotle M Mannan , Griselda Metta Yvone , Kenneth N Ross
Nature Biotechnology 34 ( 4) 419 -423
226
2016
Characterizing genomic alterations in cancer by complementary functional associations
Jong Wook Kim , Olga B Botvinnik , Omar Abudayyeh , Chet Birger
Nature Biotechnology 34 ( 5) 539 -546
66
2016
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies
Glenn S Cowley , Barbara A Weir , Francisca Vazquez , Pablo Tamayo
Scientific Data 1 ( 1) 140035 -140035
418
2014
Allele-specific amplification in cancer revealed by SNP array analysis.
Thomas LaFramboise , Barbara A Weir , Xiaojun Zhao , Rameen Beroukhim
PLOS Computational Biology 1 ( 6) 507 -517
116
2005
Absolute quantification of somatic DNA alterations in human cancer
Scott L Carter , Kristian Cibulskis , Elena Helman , Aaron McKenna
Nature Biotechnology 30 ( 5) 413 -421
1,766
2012
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
Adam J Bass , Hideo Watanabe , Craig H Mermel , Soyoung Yu
Nature Genetics 41 ( 11) 1238 -1242
994
2009
Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.
Jordi Barretina , Barry S Taylor , Shantanu Banerji , Alexis H Ramos
Nature Genetics 42 ( 8) 715 -721
487
2010