Leopold Kong
机构: The U.S. Food and Drug Administration
每年引用次数
引用次数
引用: 5,087
H-指数: 34
I10-指数 : 35
出版物: 40
The proteoglycan brevican binds to fibronectin after proteolytic cleavage and promotes glioma cell motility
Bin Hu , Leopold L. Kong , Russell T. Matthews , Mariano S. Viapiano
Journal of Biological Chemistry 283 ( 36) 24848 -24859
116
2008
Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors
Fernando Aleman , Netanel Tzarum , Leopold Kong , Kenna Nagy
Proceedings of the National Academy of Sciences of the United States of America 115 ( 29) 7569 -7574
9
2018
Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies
Netanel Tzarum , Erick Giang , Leopold Kong , Linling He
Science Advances 5 ( 1)
40
2019
Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.
Leopold Kong , Alba Torrents de la Peña , Marc C. Deller , Fernando Garces
Acta Crystallographica Section D-biological Crystallography 71 ( 10) 2099 -2108
63
2015
Capitalizing on knowledge of hepatitis C virus neutralizing epitopes for rational vaccine design.
Leopold Kong , Kelli N Jackson , Ian A Wilson , Mansun Law
Current Opinion in Virology 11 148 -157
32
2015
Expression-System-Dependent Modulation of HIV-1 Envelope Glycoprotein Antigenicity and Immunogenicity
Leopold Kong , Neil C. Sheppard , Guillaume B.E. Stewart-Jones , Cynthia L. Robson
Journal of Molecular Biology 403 ( 1) 131 -147
76
2010
Molecular Recognition of HIV Glycans by Antibodies
Leopold Kong , Robyn L. Stanfield , Ian A. Wilson
Springer, New York, NY 117 -141
6
2014
Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.
Leopold Kong , Bin Ju , Yajing Chen , Linling He
Immunity 44 ( 4) 939 -950
78
2016
Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch
Daniel T. MacLeod , Nancy M. Choi , Bryan Briney , Fernando Garces
Immunity 44 ( 5) 1215 -1226
101
2016
A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure
Jeong Hyun Lee , Raiees Andrabi , Ching-Yao Su , Anila Yasmeen
Immunity 46 ( 4) 690 -702
132
2017
Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans
Fernando Garces , Jeong Hyun Lee , Natalia de Val , Alba Torrents de la Pena
Immunity 43 ( 6) 1053 -1063
212
2015
Protein stability: a crystallographer's perspective.
Marc C. Deller , Leopold Kong , Bernhard Rupp
Acta Crystallographica Section F-structural Biology and Crystallization Communications 72 ( 2) 72 -95
74
2016
Approaching rational epitope vaccine design for hepatitis C virus with meta-server and multivalent scaffolding
Linling He , Yushao Cheng , Leopold Kong , Parisa Azadnia
Scientific Reports 5 ( 1) 12501 -12501
67
2015
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
Leopold Kong , Jeong Hyun Lee , Katie J Doores , Charles D Murin
Nature Structural & Molecular Biology 20 ( 7) 796 -803
271
2013
Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows
Devin Sok , Khoa M Le , Melissa Vadnais , Karen L Saye-Francisco
Nature 548 ( 7665) 108 -111
86
2017
Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262.
Leopold Kong , Ian A. Wilson , Peter D. Kwong
Proteins 83 ( 3) 590 -596
33
2015
Two classes of broadly neutralizing antibodies within a single lineage directed to the high-mannose patch of HIV Envelope
Katie J. Doores , Leopold Kong , Stefanie A. Krumm , Khoa M. Le
Journal of Virology 89 ( 2) 1105 -1118
63
2015
Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic Sequon
Wentao Chen , Leopold Kong , Stephen Connelly , Julia M. Dendle
ACS Chemical Biology 11 ( 7) 1852 -1861
39
2016
Cryo-EM of the dynamin polymer assembled on lipid membrane
Leopold Kong , Kem A. Sochacki , Huaibin Wang , Shunming Fang
Nature 560 ( 7717) 258 -262
42
2018
Structure of hepatitis C virus envelope glycoprotein E1 antigenic site 314-324 in complex with antibody IGH526
Leopold Kong , Rameshwar U. Kadam , Erick Giang , Tinashe B. Ruwona
Journal of Molecular Biology 427 ( 16) 2617 -2628
30
2015