Jan Passchier
机构: Director of Operations and Head of Preclinical Sciences, Imanova Ltd
主页: imanova.co.uk
每年引用次数
引用次数
引用: 4,133
H-指数: 34
I10-指数 : 56
出版物: 165
First evaluation of PET-based human biodistribution and radiation dosimetry of 11C-BU99008, a tracer for imaging the imidazoline2 binding site.
Ashwin V. Venkataraman , Nicholas Keat , James F. Myers , Samuel Turton
EJNMMI research 8 ( 1) 71
2018
Characterization of 3 PET Tracers for Quantification of Mitochondrial and Synaptic Function in Healthy Human Brain: 18F-BCPP-EF, 11C-SA-4503, and 11C-UCB-J.
Ayla Mansur , Eugenii A Rabiner , Robert A Comley , Yvonne Lewis
The Journal of Nuclear Medicine 61 ( 1) 96 -103
21
2020
Fully automated synthesis of the M1 receptor agonist [11C]GSK1034702 for clinical use on an Eckert & Ziegler Modular Lab system
Mickael Huiban , Sabina Pampols-Maso , Jan Passchier
Applied Radiation and Isotopes 69 ( 10) 1390 -1394
11
2011
Automated preparation of the dopamine D2/3 receptor agonist ligand [11C]-(+)-PHNO for human PET imaging studies
Christophe Plisson , Mickael Huiban , Sabina Pampols-Maso , Görkem Singleton
Applied Radiation and Isotopes 70 ( 2) 380 -387
9
2012
Rapid multiphase carbonylation reactions by using a microtube reactor: applications in positron emission tomography 11C-radiolabeling.
Philip W. Miller , Nicholas J. Long , Andrew J. de Mello , Ramon Vilar
Angewandte Chemie 46 ( 16) 2875 -2878
108
2007
Use of carbon-11 labelled tool compounds in support of drug development.
Giulia Boscutti , Mickael Huiban , Jan Passchier
Drug Discovery Today: Technologies 25 3 -10
7
2017
Uptake and regional distribution of [11C]rofecoxib in human brain
Robert A. Comley , Jan Passchier , Anton Willemsen , Anders Wall
NeuroImage 52
2
2010
Enhanced copper-mediated 18F-fluorination of aryl boronic esters provides eight radiotracers for PET applications
Sean Preshlock , Samuel Calderwood , Stefan Verhoog , Matthew Tredwell
Chemical Communications 52 ( 54) 8361 -8364
77
2016
DREADD Activation of Pedunculopontine Cholinergic Neurons Reverses Motor Deficits and Restores Striatal Dopamine Signaling in Parkinsonian Rats.
Puneet K. Sharma , Lisa Wells , Gaia Rizzo , Joanna L. Elson
Neurotherapeutics 17 ( 3) 1120 -1141
3
2020
Investigation of the Brain Biodistribution of the Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitor [18F]GSK2647544 in Healthy Male Subjects.
Mickael Huiban , Christopher Coello , Kai Wu , Yanmei Xu
Molecular Imaging and Biology 19 ( 1) 153 -161
8
2017
Preclinical In Vitro and In Vivo Characterization of Synaptic Vesicle 2A-Targeting Compounds Amenable to F-18 Labeling as Potential PET Radioligands for Imaging of Synapse Integrity.
Shil Patel , Ashley Knight , Stephen Krause , Tyler Teceno
Molecular Imaging and Biology 22 ( 4) 832 -841
20
2020
In vivo detection of cerebral tau pathology in long-term survivors of traumatic brain injury.
Nikos Gorgoraptis , Lucia M. Li , Alex Whittington , Karl A. Zimmerman
Science Translational Medicine 11 ( 508)
20
2019
In vivo Imaging of microglial activation by positron emission tomography with [11C]PBR28 in the 5XFAD model of Alzheimer’s disease
Nazanin Mirzaei , Sac Pham Tang , Sharon Ashworth , Christopher Coello
Glia 64 ( 6) 993 -1006
48
2016
Serotonin release measured in the human brain: a PET study with [ 11 C]CIMBI-36 and d-amphetamine challenge
David Erritzoe , Abhishekh H. Ashok , Graham E. Searle , Alessandro Colasanti
Neuropsychopharmacology 45 ( 5) 804 -810
9
2020
Synthesis of Carbon‐11 Labeled (+)‐4‐Propyl‐3,4,4a,5,6,10b‐Hexahydro‐2H‐Naphtho[1,2‐B][1,4]Oxazin‐9‐Ol ([11C]‐(+)‐PHNO)
Christophe Plisson , Joaquim Ramada-Magalhaes , Jan Passchier
Radiochemical Syntheses: Further Radiopharmaceuticals for Positron Emission Tomography and New Strategies for Their Production 81 -92
2015
A broadly applicable [18F]trifluoromethylation of aryl and heteroaryl iodides for PET imaging
Mickael Huiban , Matthew Tredwell , Satoshi Mizuta , Zehong Wan
Nature Chemistry 5 ( 11) 941 -944
119
2013
Quantitative imaging of 5-HT1A receptor binding in healthy volunteers with [18f]p-MPPF
Jan Passchier , Aren van Waarde , Remge M Pieterman , Philip H Elsinga
Nuclear Medicine and Biology 27 ( 5) 473 -476
32
2000
Clinical quantification of the integrin αvβ6 by [18F]FB-A20FMDV2 positron emission tomography in healthy and fibrotic human lung (PETAL Study)
Pauline T Lukey , Christopher Coello , Roger Gunn , Christine Parker
European Journal of Nuclear Medicine and Molecular Imaging 47 ( 4) 967 -979
14
2020
Preclinical evaluation of [ 18 F]FB-A20FMDV2 as a selective marker for measuring α V β 6 integrin occupancy using positron emission tomography in rodent lung
Mayca Onega , Christine A. Parker , Christopher Coello , Gaia Rizzo
European Journal of Nuclear Medicine and Molecular Imaging 47 ( 4) 958 -966
2020
Visualisation of serotonin-1A (5-HT1A) receptors in the central nervous system
Jan Passchier , Aren van Waarde
European Journal of Nuclear Medicine and Molecular Imaging 28 ( 1) 113 -129
81
2001