引用次数
引用: 1,824
H-指数: 21
I10-指数 : 30
出版物: 58
Processive phosphorylation of alternative splicing factor/splicing factor 2.
B. E. Aubol , S. Chakrabarti , J. Ngo , J. Shaffer
Proceedings of the National Academy of Sciences of the United States of America 100 ( 22) 12601 -12606
91
2003
Protein-Protein Interaction Inhibitor of SRPKs Alters the Splicing Isoforms of VEGF and Inhibits Angiogenesis.
Qiuling Xie , Jacky Chi Ki Ngo , Chuyue Zeng , Kristen Wing Yu Yung
iScience 24 ( 5) 102423 -102423
2021
CAG RNAs induce DNA damage and apoptosis by silencing NUDT16 expression in polyglutamine degeneration.
Matthew Ho Yan Lau , Wen Li , Jacquelyne Ka-Li Sun , Kong Hung Sze
Proceedings of the National Academy of Sciences of the United States of America 118 ( 19)
12
2021
The ribosomal maturation factor P from Mycobacterium smegmatis facilitates the ribosomal biogenesis by binding to the small ribosomal protein S12
Tinyi Chu , Xing Weng , Carmen Oi Kwan Law , Hoi-Kuan Kong
Journal of Biological Chemistry 294 ( 1) 372 -378
4
2019
Distinct mechanisms govern the phosphorylation of different SR protein splicing factors
Yunxin Long , Weng Hong Sou , Kristen Wing Yu Yung , Haizhen Liu
Journal of Biological Chemistry 294 ( 4) 1312 -1327
21
2019
AQAMAN, a bisamidine-based inhibitor of toxic protein inclusions in neurons, ameliorates cytotoxicity in polyglutamine disease models
Huiling Hong , Alex Chun Koon , Zhefan Stephen Chen , Yuming Wei
Journal of Biological Chemistry 294 ( 8) 2757 -2770
7
2019
A Peptidylic Inhibitor for Neutralizing r(GGGGCC)exp-Associated Neurodegeneration in C9ALS-FTD.
Qian Zhang , Ying An , Zhefan Stephen Chen , Alex Chun Koon
Molecular therapy. Nucleic acids 16 172 -185
4
2019
Structural basis for therapeutic intervention of uPA/uPAR system
Jacky Chi Ki Ngo , Longguang Jiang , Zhonghui Lin , Cai Yuan
Current Drug Targets 12 ( 12) 1729 -1743
22
2011
Adaptable molecular interactions guide phosphorylation of the SR protein ASF/SF2 by SRPK1.
Jonathan C. Hagopian , Chen-Ting Ma , Bryan R. Meade , Claudio P. Albuquerque
Journal of Molecular Biology 382 ( 4) 894 -909
40
2008
Brain-Targeting Delivery of Two Peptidylic Inhibitors for Their Combination Therapy in Transgenic Polyglutamine Disease Mice via Intranasal Administration.
Mengbi Yang , Qian Zhang , Qianwen Wang , Kasper K. Sørensen
Molecular Pharmaceutics 15 ( 12) 5781 -5792
3
2018
A peptidylic inhibitor for neutralizing expanded CAG RNA-induced nucleolar stress in polyglutamine diseases.
Qian Zhang , Zhefan Stephen Chen , Ying An , Haizhen Liu
RNA 24 ( 4) 486 -498
10
2018
SR protein kinase 1 is resilient to inactivation.
Jacky Chi Ki Ngo , Justin Gullingsrud , Kayla Giang , Melinda Jean Yeh
Structure 15 ( 1) 123 -133
24
2007
Crystal Structure of Human Factor VIII: Implications for the Formation of the Factor IXa-Factor VIIIa Complex
Jacky Chi Ki Ngo , Mingdong Huang , David A. Roth , Barbara C. Furie
Structure 16 ( 4) 597 -606
200
2008
Neuronal adaptor FE65 stimulates Rac1-mediated neurite outgrowth by recruiting and activating ELMO1.
Wen Li , Ka Ming Vincent Tam , Wai Wa Ray Chan , Alex Chun Koon
Journal of Biological Chemistry 293 ( 20) 7674 -7688
7
2018
GULP1/CED-6 ameliorates amyloid-β toxicity in a Drosophila model of Alzheimer’s disease
Wai Yin Vivien Chiu , Alex Chun Koon , Jacky Chi Ki Ngo , Ho Yin Edwin Chan
Oncotarget 8 ( 59) 99274 -99283
5
2017
Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1.
Baoyu Zhao , Cai Yuan , Rui Li , Dan Qu
Journal of Biological Chemistry 288 ( 16) 11155 -11164
27
2013
Regulation of Tissue Factor Activity: Conformational Changes in Tissue Factor Associated with Cleavage of the Cysteine 186-Cysteine 209 Disulfide Bond.
Jacky Chi Ki Ngo , Margaret Jacobs , Barbara C. Furie , Bruce Furie
Blood 110 ( 11) 270 -270
1
2007
SRPKIN-1: A Covalent SRPK1/2 Inhibitor that Potently Converts VEGF from Pro-angiogenic to Anti-angiogenic Isoform
John M. Hatcher , Guowei Wu , Chuyue Zeng , Jie Zhu
Chemistry & Biology 25 ( 4) 460
91
2018
A brain-targeting lipidated peptide for neutralizing RNA-mediated toxicity in Polyglutamine Diseases.
Qian Zhang , Mengbi Yang , Kasper K. Sørensen , Charlotte S. Madsen
Scientific Reports 7 ( 1) 12077
5
2017
Planar cell polarity gene Fuz triggers apoptosis in neurodegenerative disease models.
Zhefan Stephen Chen , Li Li , Shaohong Peng , Francis M Chen
EMBO Reports 19 ( 9)
8
2018