Metal–polybenzimidazole complexes as a nonviral gene carrier: Effects of the DNA affinity on gene delivery

作者: Xueying Huang , Xiongwei Dong , Xue Li , Xianggao Meng , Dan Zhang

DOI: 10.1016/J.JINORGBIO.2013.09.009

关键词: TransfectionIsothermal titration calorimetryCytotoxicityGene deliveryMetalTitrationBiochemistryInternalizationChemistryBiophysicsDNA

摘要: … and gene transfection efficacy of metal complexes is explored … complexes of divalent metal cations Co 2 + and Ca 2 + . … 40 μM plasmid DNA and each of the metal complexes at varied …

参考文章(63)
Xia Guo, Leaf Huang, Recent advances in nonviral vectors for gene delivery Accounts of Chemical Research. ,vol. 45, pp. 971- 979 ,(2012) , 10.1021/AR200151M
Jonathan Widom, Robert L. Baldwin, Cation-induced toroidal condensation of DNA studies with Co3+(NH3)6. Journal of Molecular Biology. ,vol. 144, pp. 431- 453 ,(1980) , 10.1016/0022-2836(80)90330-7
Dan Luo, W. Mark Saltzman, Synthetic DNA delivery systems Nature Biotechnology. ,vol. 18, pp. 33- 37 ,(2000) , 10.1038/71889
Mahmoud Soliman, Stephanie Allen, Martyn C. Davies, Cameron Alexander, Responsive polyelectrolyte complexes for triggered release of nucleic acid therapeutics. Chemical Communications. ,vol. 46, pp. 5421- 5433 ,(2010) , 10.1039/C0CC00794C
Xindian Dong, Xiaoyong Wang, Yafeng He, Zhen Yu, Miaoxin Lin, Changli Zhang, Jing Wang, Yajie Song, Yangmiao Zhang, Zhipeng Liu, Yizhi Li, Zijian Guo, Reversible DNA Condensation Induced by a Tetranuclear Nickel(II) Complex Chemistry: A European Journal. ,vol. 16, pp. 14181- 14189 ,(2010) , 10.1002/CHEM.201001457
Santanu Bhattacharya, Avinash Bajaj, Advances in gene delivery through molecular design of cationic lipids Chemical Communications. pp. 4632- 4656 ,(2009) , 10.1039/B900666B
Hong Ding, Ken-Tye Yong, Indrajit Roy, Haridas E. Pudavar, Wing Cheung Law, Earl J. Bergey, Paras N. Prasad, Gold Nanorods Coated with Multilayer Polyelectrolyte as Contrast Agents for Multimodal Imaging Journal of Physical Chemistry C. ,vol. 111, pp. 12552- 12557 ,(2007) , 10.1021/JP0733419
Meredith A. Mintzer, Eric E. Simanek, Nonviral Vectors for Gene Delivery Chemical Reviews. ,vol. 109, pp. 259- 302 ,(2009) , 10.1021/CR800409E
Polina Ilina, Zanna Hyvonen, Maeva Saura, Kirsten Sandvig, Marjo Yliperttula, Marika Ruponen, Genetic blockage of endocytic pathways reveals differences in the intracellular processing of non-viral gene delivery systems. Journal of Controlled Release. ,vol. 163, pp. 385- 395 ,(2012) , 10.1016/J.JCONREL.2012.09.016
Karina Kizjakina, Joshua M. Bryson, Giovanna Grandinetti, Theresa M. Reineke, Cationic glycopolymers for the delivery of pDNA to human dermal fibroblasts and rat mesenchymal stem cells. Biomaterials. ,vol. 33, pp. 1851- 1862 ,(2012) , 10.1016/J.BIOMATERIALS.2011.10.031