Long-term valuation of oral mavacoxib in osteoarthrosic dogs using force platform analysis.

摘要: Received: Revised: Accepted: October 11, 2012 December 12, 17, The aim of this study was to assess the efficacy mavacoxib, a cox-2 inhibitor, improve peak vertical force (PVF) and impulse (VI) lame clientowned dogs with severe coxofemoral osteoarthrosis (OA) by using platform. A group ten canarian presa lameness pain for due hip dysplasia were used study. Five additional sound same breed as control groups. single platform register forces mounted in 7 m runway. Mean (± SD) values speed 1.6±0.5 m/s. Data corresponding 5 valid trials recorded at walk day 0, 7, 60 180 after starting treatment procedure. dosing regimen consisted loading oral dose 2 mg⁄ kg be repeated 14 days, thereafter interval 1 month. OA showed significant improvement PVF two months about 7% bm exerted diseased limbs VI 1.6% limbs. This clearly that treated mavacoxib increased over time, soon seven days medical therapy, demonstrating high potential clinical use associated joint. ©2012 PVJ. All rights reserved