Toxic epidermal necrolysis‐like reaction secondary to colchicine overdose

作者: M.P. Arroyo , S. Sanders , H. Yee , D. Schwartz , H. Kamino

DOI: 10.1111/J.1365-2133.2004.05838.X

关键词: ErythrodermaDermatologyColchicineToxicityFamilial Mediterranean feverDrugGoutExanthemToxic epidermal necrolysisMedicine

摘要: Colchicine is a microtubule-inhibiting drug used to treat gout, familial Mediterranean fever and many other skin diseases. Intoxication with colchicine affects multiple organs, often fatally. Cutaneous sequelae of toxicity are rare. We describe the clinical histological features toxic epidermal necrolysis-like exanthem in patient who lethally overdosed on colchicine.

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