Diagnosis of malaria: a review of alternatives to conventional microscopy.

摘要: Malaria causes significant morbidity and mortality worldwide, including countries with mainly imported malaria. In developing nations, scarce resources lead to inadequate diagnostic procedures. affluent countries, poor familiarity malaria may cause clinical laboratory misdiagnosis. Microscopy of Giemsa-stained thick thin films remains the current standard for diagnosis. Although it has good sensitivity allows species identification parasite counts, is time consuming, requires microscopical expertise maintenance equipment. fluorescent stains (QBC), dipstick antigen detection HRP2 pLDH (Parasight-F, ICT Pf, OptiMAL), polymerase chain reaction assays some automated blood cell analysers offer new approaches are reviewed here, emphasis on relevance their potential complement conventional microscopy, especially in