Translating peptides into small molecules
作者： Gerd Hummel , Ulrich Reineke , Ulf Reimer
DOI: 10.1039/B611791K
关键词: Biophysics 、 Small molecule 、 Chemistry
摘要:
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sci-hub.se 参考文章(25)
Albert Loffet, Peptides as Drugs: Is There a Market?† Journal of Peptide Science. ,vol. 8, pp. 1- 7 ,(2002) , 10.1002/PSC.366
Michael Kahn, Peptide Secondary Structure Mimetics: Recent Advances and Future Challenges Synlett. ,vol. 1993, pp. 821- 826 ,(1993) , 10.1055/S-1993-22619
Yasunobu Takano, Masahiro Koizumi, Reiko Takarada, Midori Takimoto Kamimura, Ryszard Czerminski, Tohru Koike, Computer-aided design of a factor Xa inhibitor by using MCSS functionality maps and a CAVEAT linker search Journal of Molecular Graphics & Modelling. ,vol. 22, pp. 105- 114 ,(2003) , 10.1016/S1093-3263(03)00140-2
W.C. Ripka, G.V. De Lucca, A.C. Bach, R.S. Pottorf, J.M. Blaney, Protein β-turn mimetics I. Design, synthesis, and evaluation in model cyclic peptides. Tetrahedron. ,vol. 49, pp. 3593- 3608 ,(1993) , 10.1016/S0040-4020(01)90217-0
Kit S. Lam, Sydney E. Salmon, Evan M. Hersh, Victor J. Hruby, Wieslaw M. Kazmierski, Richard J. Knapp, A new type of synthetic peptide library for identifying ligand-binding activity Nature. ,vol. 354, pp. 82- 84 ,(1992) , 10.1038/354082A0
J. Scott, G. Smith, Searching for Peptide Ligands With an Epitope Library Science. ,vol. 249, pp. 386- 390 ,(1990) , 10.1126/SCIENCE.1696028
Stefanie Flohr, Michael Kurz, Evi Kostenis, Alexandre Brkovich, Alain Fournier, Thomas Klabunde, Identification of Nonpeptidic Urotensin II Receptor Antagonists by Virtual Screening Based on a Pharmacophore Model Derived from Structure−Activity Relationships and Nuclear Magnetic Resonance Studies on Urotensin II Journal of Medicinal Chemistry. ,vol. 45, pp. 1799- 1805 ,(2002) , 10.1021/JM0111043
Peter N Lewis, Frank A Momany, Harold A Scheraga, Chain reversals in proteins Biochimica et Biophysica Acta. ,vol. 303, pp. 211- 229 ,(1973) , 10.1016/0005-2795(73)90350-4
R. W. Roberts, J. W. Szostak, RNA-peptide fusions for the in vitro selection of peptides and proteins Proceedings of the National Academy of Sciences of the United States of America. ,vol. 94, pp. 12297- 12302 ,(1997) , 10.1073/PNAS.94.23.12297
L. C. Mattheakis, R. R. Bhatt, W. J. Dower, An in vitro polysome display system for identifying ligands from very large peptide libraries Proceedings of the National Academy of Sciences of the United States of America. ,vol. 91, pp. 9022- 9026 ,(1994) , 10.1073/PNAS.91.19.9022