The Role of Cardiolipin Remodeling in Mitochondrial Function and Human Diseases
作者： Yan Yan , Bin Kang
DOI: 10.5539/JMBR.V2N1P1
关键词: Enzyme 、 Cardiolipin 、 Cell biology 、 Biochemistry 、 Biology 、 Function (biology) 、 Mitochondrion
摘要: Cardiolipin (CL), one of bisphosphatidyl glycerol lipid, is found to contain high level C18:2 acyl chains and exist exclusively in inner membranes mitochondria. remodeling the process for CL attain its specific chains. With purpose introducing this interesting field readers, review, we elucidate role cardiolipin normal functions mitochondria by analyzing physical chemical characters cardiolipin; introduce current models enzymes involved process; reviewed latest progress clinical implications remodeling.
sci-hub.se 参考文章(67)
Andreas Beranek, Gerald Rechberger, Heide Knauer, Heimo Wolinski, Sepp. D. Kohlwein, Regina Leber, Identification of a Cardiolipin-specific Phospholipase Encoded by the Gene CLD1 (YGR110W) in Yeast Journal of Biological Chemistry. ,vol. 284, pp. 11572- 11578 ,(2009) , 10.1074/JBC.M805511200
Albert W. Girotti, Tamas Kriska, Role of Lipid Hydroperoxides in Photo-Oxidative Stress Signaling Antioxidants & Redox Signaling. ,vol. 6, pp. 301- 310 ,(2004) , 10.1089/152308604322899369
Derek K. Zachman, Adam J. Chicco, Sylvia A. McCune, Robert C. Murphy, Russell L. Moore, Genevieve C. Sparagna, The role of calcium-independent phospholipase A2 in cardiolipin remodeling in the spontaneously hypertensive heart failure rat heart Journal of Lipid Research. ,vol. 51, pp. 525- 534 ,(2010) , 10.1194/JLR.M000646
B. Rüstow, M. Schlame, H. Rabe, G. Reichmann, D. Kunze, Species pattern of phosphatidic acid, diacylglycerol, CDP-diacylglycerol and phosphatidylglycerol synthesized de novo in rat liver mitochondria Biochimica et Biophysica Acta. ,vol. 1002, pp. 261- 263 ,(1989) , 10.1016/0005-2760(89)90296-8
William A. Taylor, Grant M. Hatch, Purification and characterization of monolysocardiolipin acyltransferase from pig liver mitochondria Journal of Biological Chemistry. ,vol. 278, pp. 12716- 12721 ,(2003) , 10.1074/JBC.M210329200
Yang Xu, Ashim Malhotra, Mindong Ren, Michael Schlame, The Enzymatic Function of Tafazzin Journal of Biological Chemistry. ,vol. 281, pp. 39217- 39224 ,(2006) , 10.1074/JBC.M606100200
Michael Schlame, Jeffrey A. Towbin, Paul M. Heerdt, Roswitha Jehle, Salvatore DiMauro, Thomas J. J. Blanck, Deficiency of tetralinoleoyl-cardiolipin in Barth syndrome. Annals of Neurology. ,vol. 51, pp. 634- 637 ,(2002) , 10.1002/ANA.10176
Xiong Su, Xianlin Han, David J. Mancuso, Dana R. Abendschein, Richard W. Gross, Accumulation of long-chain acylcarnitine and 3-hydroxy acylcarnitine molecular species in diabetic myocardium: identification of alterations in mitochondrial fatty acid processing in diabetic myocardium by shotgun lipidomics. Biochemistry. ,vol. 44, pp. 5234- 5245 ,(2005) , 10.1021/BI047773A
G M Hatch, Cardiolipin: biosynthesis, remodeling and trafficking in the heart and mammalian cells (Review). International Journal of Molecular Medicine. ,vol. 1, pp. 33- 74 ,(1998) , 10.3892/IJMM.1.1.33
Baltazar Gomez, Neal C. Robinson, Phospholipase digestion of bound cardiolipin reversibly inactivates bovine cytochrome bc1. Biochemistry. ,vol. 38, pp. 9031- 9038 ,(1999) , 10.1021/BI990603R