Clinicopathological analysis of primary splenic diffuse large B-cell lymphoma

作者: Joji Shimono , Hiroaki Miyoshi , Junichi Kiyasu , Kensaku Sato , Tomohiko Kamimura

DOI: 10.1111/BJH.14736

关键词: Survival analysisPathologyCD5Splenic LymphomaRed pulpB symptomsLymphomaDiffuse large B-cell lymphomaWhite pulpMedicine

摘要: Splenic infiltration is often seen in diffuse large B‐cell lymphoma (DLBCL). However, primary splenic DLBCL is rare and studies on its clinicopathological features are limited. We assessed 66 cases of primary splenic DLBCL and 309 control DLBCL, not otherwise specified. Hepatitis C virus antibody prevalence, B symptoms, poor performance status and CD 5 positivity differed significantly between the primary splenic DLBCL and control DLBCL groups. Primary splenic DLBCL cases were classified histopathologically into two groups …

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