Methods for modifying the production of a polypeptide
作者： Kim Hansen , Deborah S. Yaver , Michael Lamsa , Howard Brody
DOI:
关键词: Mutant cell 、 Genome 、 Nucleic acid 、 Molecular biology 、 Biochemistry 、 DNA sequencing 、 Cell 、 Locus (genetics) 、 A-DNA 、 Biology
摘要: The present invention relates to methods for modifying the production of a polypeptide, comprising: (a) introducing nucleic acid construct into cell, wherein cell comprises DNA sequence encoding under conditions in which integrates genome at locus not within polypeptide produce mutant integration modifies by relative when and are cultured same conditions; (b) identifying with modified polypeptide.
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